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Gene · 84909

AOPEP: aminopeptidase O (putative)

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. AOPEP: aminopeptidase O (putative). Genes, record 84909. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/84909

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
AOPEP
HGNC
Name
aminopeptidase O (putative)
HGNC
NCBI Gene ID
84909
NCBI Gene
HGNC ID
HGNC:1361
HGNC
Ensembl
ENSG00000148120
NCBI Gene
Aliases
AP-O, APO, C90RF3, C9orf3, DYT31, FLJ14675, ONPEP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8N6M6Aminopeptidase O8190Ensembl, GeneID, HGNC

Source UniProt

Patents15

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-199604Q8N6M6Espacenet
EP 4640849 A22025-10-291449Q8N6M6Espacenet
EP 4641201 A22025-10-299860Q8N6M6Espacenet
JP 2025519096 A2025-06-241449Q8N6M6Espacenet
JP 2025517969 A2025-06-129860Q8N6M6Espacenet
JP 2025517970 A2025-06-129604Q8N6M6Espacenet
JP 2025024198 A2025-02-1910947Q8N6M6Espacenet
US 11446398 B22022-09-2017045Q8N6M6Espacenet
JP 2022524081 A2022-04-27120016Q8N6M6Espacenet
US 9827332 B22017-11-2810947Q8N6M6Espacenet

1 to 10 of 15

See all 15 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
TOSEDOSTATCHEMBL2103847Aminopeptidase inhibitorINHIBITOR

Source ChEMBL

Trials9

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02452346TOSEDOSTATPHASE22018-06-12ClinicalTrials.gov
NCT02352831TOSEDOSTATPHASE1/PHASE22018-12-17ClinicalTrials.gov
NCT01636609TOSEDOSTATPHASE1ClinicalTrials.gov
NCT01567059TOSEDOSTATPHASE2ClinicalTrials.gov
NCT01180426TOSEDOSTATPHASE2ClinicalTrials.gov
NCT00780598TOSEDOSTATPHASE2ClinicalTrials.gov
NCT00737555TOSEDOSTATPHASE1ClinicalTrials.gov
NCT00689000TOSEDOSTATPHASE1/PHASE2ClinicalTrials.gov
NCT00522938TOSEDOSTATPHASE1/PHASE2ClinicalTrials.gov

NIH grants3,351

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA008748Cancer Center Support Grant112025
R01HL092577IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL112025
P30CA016672Cancer Center Support Grant102025
P30DK063491Diabetes Research Center (DRC)102025
P30GM124165NE-CAT: A Resource for Advanced Macromolecular Crystallography102025
P30CA021765Cancer Center Support Grant (CCSG)92025
ZICES103326NIEHS Cryo-EM Core Facility62025
P01CA092584Structural Cell Biology of DNA Repair Machines52025
P30CA016086Cancer Center Support Grant52025
P30CA068485Cancer Center Support Grant52025

1 to 10 of 3,351Source NIH's project files

See all 3,351 nih grants

Papers4,394

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42770110PubTator, text miningPubMed
42769471PubTator, text miningPubMed
42723553PubTator, text miningPubMed
42669304PubTator, text miningPubMed
42587803PubTator, text miningPubMed
42435666PubTator, text miningPubMed
42415160PubTator, text miningPubMed
42404086PubTator, text miningPubMed
42366520PubTator, text miningPubMed
42337705PubTator, text miningPubMed

1 to 10 of 4,394

See all 4,394 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/84909

GET https://conductscience.org/api/genes/v1/84909/patents