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Gene · 8519

IFITM1: interferon induced transmembrane protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IFITM1: interferon induced transmembrane protein 1. Genes, record 8519. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8519

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Gene

Symbol
IFITM1
HGNC
Name
interferon induced transmembrane protein 1
HGNC
NCBI Gene ID
8519
NCBI Gene
HGNC ID
HGNC:5412
HGNC
Ensembl
ENSG00000185885
NCBI Gene
Aliases
9-27, CD225, DSPA2a, IFI17, LEU13
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P13164Interferon-induced transmembrane protein 11250Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1450046P13164Espacenet
JP 2026004568 A2026-01-1450047P13164Espacenet
JP 2026004568 A2026-01-1450049P13164Espacenet
EP 4650780 A22025-11-195874P13164Espacenet
EP 4641202 A22025-10-29315P13164Espacenet
JP 2025529142 A2025-09-042037P13164Espacenet
US 12371689 B22025-07-292037P13164Espacenet
JP 2025517970 A2025-06-125874P13164Espacenet
KR 1020250017231 A2025-02-04315P13164Espacenet
US 12024722 B22024-07-0262P13164Espacenet

1 to 10 of 35

See all 35 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,211

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIFITM1 papersNewest fiscal year
P30CA016672Cancer Center Support Grant112025
P30CA008748Cancer Center Support Grant92025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital92025
P30CA016086Cancer Center Support Grant72025
P30CA168524The University of Kansas Cancer Center72025
UL1TR001863Yale Clinical and Translational Science Award72025
ZIABC011779Mechanisms of Virus Entry into Cells and Antiviral Barriers Limiting Entry72025
P30AI036214San Diego Center for AIDS Research (SD CFAR)62025
P51OD011132Emory National Primate Research Center62025
R01AI130110Mechanisms of innate resistance to virus infections62025

1 to 10 of 2,211Source NIH's project files

See all 2,211 nih grants

Papers2,758

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Single-cell and bulk transcriptomic analyses define an IFI27-centered interferon-response epithelial state in bladder cancer and its transcriptional response to irradiation.Front Cell Dev Biol202642798643PubTator, text miningPubMed
Transcriptomic characterization of transitional B cells reveals four subsets with perturbed activation profiles in scleroderma.iScience202642774868PubTator, text miningPubMed
Identification of Critical Genes for Recurrent Aphthous Ulcer by Transcriptome Data Analysis and Mendelian Randomization.Oral Health Prev Dent202642714320PubTator, text miningPubMed
IFITM1 enhances anti-tumor function of unconventional TCRαβ double negative T cells by upregulating mitophagy.Sci China Life Sci202642667541PubTator, text miningPubMed
A Multi-Layered Proteogenomic Framework for the Prioritization of Cell Surface Therapeutic Targets: Proof-of-Concept for Metastatic Colorectal Cancer.Cancers (Basel)202642649884PubTator, text miningPubMed
Systems pharmacology reveals type I interferon and myeloid-like B cell reprogramming as candidate druggable axes in antiphospholipid syndrome.PLoS One202642647509PubTator, text miningPubMed
Interferon-induced transmembrane (IFITM) proteins at the tumour-immune interface: A four-axis framework for their context-dependent roles.Clin Transl Med202642613969PubTator, text miningPubMed
Retraction notice to "The role and mechanism of IFITM1 in developing acquired cisplatin resistance in small cell lung cancer" [Heliyon 10 (2024) e30806].Heliyon202642581850PubTator, text miningPubMed
Screening for candidate genes and cell populations associated with atherosclerotic calcification using single-cell RNA sequencing.Mamm Genome202642581084PubTator, text miningPubMed
Determinants of response to neoadjuvant chemotherapy in breast cancer: Integrated roles of immune pathways, DNA damage response, and cell cycle regulators.Mol Biol Rep202642530655PubTator, text miningPubMed

1 to 10 of 2,758

See all 2,758 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8519

GET https://conductscience.org/api/genes/v1/8519/patents?page=2