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Gene · 8536

CAMK1: calcium/calmodulin dependent protein kinase I

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CAMK1: calcium/calmodulin dependent protein kinase I. Genes, record 8536. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8536

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Gene

Symbol
CAMK1
HGNC
Name
calcium/calmodulin dependent protein kinase I
HGNC
NCBI Gene ID
8536
NCBI Gene
HGNC ID
HGNC:1459
HGNC
Ensembl
ENSG00000134072
NCBI Gene
Aliases
CAMKI, CaMKI, CaMKI-alpha
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q14012Calcium/calmodulin-dependent protein kinase type 13704Ensembl, GeneID, HGNC

Source UniProt

Patents41

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1439688Q14012Espacenet
EP 4650780 A22025-11-191583Q14012Espacenet
EP 4641202 A22025-10-294481Q14012Espacenet
JP 2025529142 A2025-09-04719Q14012Espacenet
US 12371689 B22025-07-29719Q14012Espacenet
JP 2025517970 A2025-06-121583Q14012Espacenet
JP 2025062604 A2025-04-1410883Q14012Espacenet
KR 1020250017231 A2025-02-044481Q14012Espacenet
JP 2024510911 A2024-03-1247Q14012Espacenet
KR 1020230152070 A2023-11-0247Q14012Espacenet

1 to 10 of 41

See all 41 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants909

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCAMK1 papersNewest fiscal year
R01DK043140Mechanisms Leading to Adrenal Zonation52025
R01ES014901Molecular and Cellular Basis of PCB Developmental Neurotoxicity52025
P30CA016672Cancer Center Support Grant42025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant42025
P40OD010440Caenorhabditis Genetics Center32025
R01HL096376E3 Ligase-Mediated Immunosuppression in Acute Lung Injury32025
R01HL097376Sepsis-Associated Immune Suppression and F-box Proteins32025
P30CA014051Cancer Center Support (Core) Grant22025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant22025
P30CA043703Case Comprehensive Cancer Center Support Grant22025

1 to 10 of 909Source NIH's project files

See all 909 nih grants

Papers1,017

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Activation phosphorylation and dephosphorylation dynamics of Ca2+/Calmodulin-dependent protein kinase Iα in HeLa cells.Cell Calcium202642641287PubTator, text miningPubMed
Delta-Band Dynamics of CaMKI-Positive Preoptic Neurons Encode Thermal Homeostatic Information.Neurosci Bull202642587252PubTator, text miningPubMed
Integrative Multiomics and Single-cell Profiling Identify Cell-type-resolved Inflammatory Drivers in Symptomatic Irreversible Pulpitis.J Endod202642486295PubTator, text miningPubMed
CAMK1 Suppresses Anoikis Resistance and Liver Metastasis in Colorectal Cancer.FASEB J202642175534PubTator, text miningPubMed
The Chemistry and Pharmacology of the Alkaloid Barettin and Its Analogues from the Marine Sponge Geodia barretti: Progress and Perspectives.Mar Drugs202641892969PubTator, text miningPubMed
GPER1 reduces skin inflammation by inhibiting keratinocyte proliferation.Cell Death Discov202641862447PubTator, text miningPubMed
Dysregulation of Protein Kinase CaMKI Leads to Autism-Related Phenotypes in Synaptic Connectivity, Sleep, Sociality, and Aging-Dependent Degeneration in Drosophila.Biology (Basel)202541007373PubTator, text miningPubMed
Machine learning-driven multi-targeted drug discovery in colon cancer using biomarker signatures.NPJ Precis Oncol202540847045PubTator, text miningPubMed
Retraction: GABA induces the differentiation of small into large cholangiocytes by activation of Ca2+/CaMK I-dependent adenylyl cyclase 8.Hepatology202540536395PubTator, text miningPubMed
Cholesterol metabolism regulated by CAMKK2-CREB signaling promotes castration-resistant prostate cancer.Cell Rep202540483692PubTator, text miningPubMed

1 to 10 of 1,017

See all 1,017 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8536

GET https://conductscience.org/api/genes/v1/8536/patents?page=2