Gene · 8536
CAMK1: calcium/calmodulin dependent protein kinase I
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CAMK1: calcium/calmodulin dependent protein kinase I. Genes, record 8536. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8536
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q14012 | Calcium/calmodulin-dependent protein kinase type 1 | 370 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents41
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 39688 | Q14012 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1583 | Q14012 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4481 | Q14012 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 719 | Q14012 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 719 | Q14012 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1583 | Q14012 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 10883 | Q14012 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4481 | Q14012 | Espacenet |
| JP 2024510911 A | 2024-03-12 | 47 | Q14012 | Espacenet |
| KR 1020230152070 A | 2023-11-02 | 47 | Q14012 | Espacenet |
1 to 10 of 41
See all 41 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants909
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CAMK1 papers | Newest fiscal year |
|---|---|---|---|
| R01DK043140 | Mechanisms Leading to Adrenal Zonation | 5 | 2025 |
| R01ES014901 | Molecular and Cellular Basis of PCB Developmental Neurotoxicity | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30CA051008 | Georgetown University Lombardi Comprehensive Cancer Center Support Grant | 4 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 3 | 2025 |
| R01HL096376 | E3 Ligase-Mediated Immunosuppression in Acute Lung Injury | 3 | 2025 |
| R01HL097376 | Sepsis-Associated Immune Suppression and F-box Proteins | 3 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 2 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 2 | 2025 |
| P30CA043703 | Case Comprehensive Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 909Source NIH's project files
See all 909 nih grantsPapers1,017
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Activation phosphorylation and dephosphorylation dynamics of Ca2+/Calmodulin-dependent protein kinase Iα in HeLa cells. | Cell Calcium | 2026 | 42641287 | PubTator, text mining | PubMed |
| Delta-Band Dynamics of CaMKI-Positive Preoptic Neurons Encode Thermal Homeostatic Information. | Neurosci Bull | 2026 | 42587252 | PubTator, text mining | PubMed |
| Integrative Multiomics and Single-cell Profiling Identify Cell-type-resolved Inflammatory Drivers in Symptomatic Irreversible Pulpitis. | J Endod | 2026 | 42486295 | PubTator, text mining | PubMed |
| CAMK1 Suppresses Anoikis Resistance and Liver Metastasis in Colorectal Cancer. | FASEB J | 2026 | 42175534 | PubTator, text mining | PubMed |
| The Chemistry and Pharmacology of the Alkaloid Barettin and Its Analogues from the Marine Sponge Geodia barretti: Progress and Perspectives. | Mar Drugs | 2026 | 41892969 | PubTator, text mining | PubMed |
| GPER1 reduces skin inflammation by inhibiting keratinocyte proliferation. | Cell Death Discov | 2026 | 41862447 | PubTator, text mining | PubMed |
| Dysregulation of Protein Kinase CaMKI Leads to Autism-Related Phenotypes in Synaptic Connectivity, Sleep, Sociality, and Aging-Dependent Degeneration in Drosophila. | Biology (Basel) | 2025 | 41007373 | PubTator, text mining | PubMed |
| Machine learning-driven multi-targeted drug discovery in colon cancer using biomarker signatures. | NPJ Precis Oncol | 2025 | 40847045 | PubTator, text mining | PubMed |
| Retraction: GABA induces the differentiation of small into large cholangiocytes by activation of Ca2+/CaMK I-dependent adenylyl cyclase 8. | Hepatology | 2025 | 40536395 | PubTator, text mining | PubMed |
| Cholesterol metabolism regulated by CAMKK2-CREB signaling promotes castration-resistant prostate cancer. | Cell Rep | 2025 | 40483692 | PubTator, text mining | PubMed |
1 to 10 of 1,017
See all 1,017 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8536
GET https://conductscience.org/api/genes/v1/8536/patents?page=2