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TSLP: thymic stromal lymphopoietin

1 protein, 167 patents, 1 drug, 42 trials, 3,407 NIH grants and 7,907 papers.

Gene 6

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTSLPHGNC
Namethymic stromal lymphopoietinHGNC
NCBI Gene ID85480NCBI Gene
HGNC IDHGNC:30743HGNC
EnsemblENSG00000145777NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q969D9Thymic stromal lymphopoietin1595Ensembl, GeneID, HGNCUniProt

Patents 167

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026131038 A2026-08-132Q969D9Espacenet
EP 4778583 A22026-07-229Q969D9Espacenet
JP 2026094137 A2026-06-092Q969D9Espacenet
JP 2026074118 A2026-05-012Q969D9Espacenet
JP 2026508389 A2026-03-1070Q969D9Espacenet
JP 2026004568 A2026-01-1467025Q969D9Espacenet
WO 2025255558 A22025-12-1163Q969D9Espacenet
WO 2025242605 A12025-11-2727Q969D9Espacenet
JP 2025170430 A2025-11-182Q969D9Espacenet
JP 2025169423 A2025-11-1227Q969D9Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
TEZEPELUMABCHEMBL3707229Thymic stromal lymphopoietin inhibitorINHIBITORChEMBL

Trials 42

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07363642TEZEPELUMABPHASE3ClinicalTrials.gov
NCT07046117TEZEPELUMABClinicalTrials.gov
NCT07015996TEZEPELUMABPHASE2ClinicalTrials.gov
NCT07013123TEZEPELUMABPHASE3ClinicalTrials.gov
NCT06951867TEZEPELUMABClinicalTrials.gov
NCT06948396TEZEPELUMABClinicalTrials.gov
NCT06883305TEZEPELUMABPHASE3ClinicalTrials.gov
NCT06878261TEZEPELUMABPHASE3ClinicalTrials.gov
NCT06740045TEZEPELUMABPHASE3ClinicalTrials.gov
NCT06705764TEZEPELUMABPHASE4ClinicalTrials.gov

NIH grants 3407

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
U19AI070235Epithelial Genes in Allergic Inflammation592,025NIH's project files
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease382,025NIH's project files
U19AI070535Airway Inflammation and Airway Remodeling in Severe Asthma272,025NIH's project files
R01AI124355Genetic and Immunological Dissection of Eosinophilic Esophagitis242,025NIH's project files
U19AI095227Viral and Host Determinants of Infant and Childhood Allergy and Asthma212,025NIH's project files
ZIAHL005409IL-2 Family Cytokines and their Receptors--Biology of the IL-7/TSLP Systems192,025NIH's project files
U01AI095608Regulation of mucosal immunity by neuronal pathways182,025NIH's project files
U19AI077439Immune-driven Airway Epithelial Dysfunction in Muco-obstructive Asthma152,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award132,025NIH's project files
P30DK050306Center for Molecular Studies in Digestive and Liver Diseases122,025NIH's project files

Papers 7907

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42821054PubTator, text miningPubMed
42818167PubTator, text miningPubMed
42816545PubTator, text miningPubMed
42814219PubTator, text miningPubMed
42806973PubTator, text miningPubMed
42805255PubTator, text miningPubMed
42805066PubTator, text miningPubMed
42802784PubTator, text miningPubMed
42801162PubTator, text miningPubMed
42798376PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license