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BHLHE40: basic helix-loop-helix family member e40
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Gene · 8553

Papers1,588

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,588

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TitleJournalYearPMIDFound bySource
When Neutrophils Do Not Die: Senescence as a New Axis of Tumor Immunosuppression.Cancer Discov202642817716PubTator, text miningPubMed
Clock-Related Genes Mark a Developmental Cortical Maturation Program Associated with Stage-Resolved Responses to Prenatal Immune Activation.Genes (Basel)202642793001PubTator, text miningPubMed
Trimester-specific associations of methyl-donor nutrients and prenatal dietary patterns with adolescent blood leukocyte circadian gene DNA methylation.J Dev Orig Health Dis202642788273PubTator, text miningPubMed
Single-cell RNA-seq analysis revealed that BHLHE40 and its binding protein THBS1 are involved in diabetic corneal epitheliopathy.Exp Eye Res202642697405PubTator, text miningPubMed
BHLHE40 and ChREBP associate with hepatic enhancer clusters containing PPARα, RXRα, and HNF4 nuclear receptors.Endocrinology202642626966PubTator, text miningPubMed
Modulation of neuronal excitability and plasticity by BHLHE41 conveys lithium non-responsiveness.Mol Psychiatry202642613416PubTator, text miningPubMed
Integrative Transcriptomics Links Dapagliflozin-Opposed Macrophage Programs to BHLHE40-Associated Regulation and NFKB1-Associated Signaling in HFpEF.OMICS202642605950PubTator, text miningPubMed
A machine learning-derived and functionally validated circadian rhythm signature predicts clinical outcomes and in silico drug sensitivity in colorectal cancer.Transl Oncol202642520477PubTator, text miningPubMed
Intratumoral Hypoxia Triggers Mitochondrial BHLHE40 ROS Sensing Pathway to Promote Radioresistance in Triple-Negative Breast Cancer.Adv Sci (Weinh)202642505118PubTator, text miningPubMed
BHLHE40/DEC1 programs epidermal Langerhans cell identity.J Invest Dermatol202642492657PubTator, text miningPubMed
Single-cell transcriptomic profiling of immune microenvironment remodeling in unresectable hepatocellular carcinoma after TACE combined therapies.Int Immunopharmacol202642480323PubTator, text miningPubMed
Identification of ITGB2, ELN, and KLRK1 as stress granule-related biomarkers of pterygium through integrated transcriptomic analysis and machine learning.Biochem Biophys Res Commun202642447550PubTator, text miningPubMed
Transcription factor BHLHE40 expression in group 3 innate lymphoid cells and RORγt⁺ antigen-presenting cells coordinates intestinal immunity.Immunity202642413497PubTator, text miningPubMed
Integrative Single-Cell and Bulk Transcriptome Analysis Reveals Molecular Mechanisms, Prognostic Signatures, and Therapeutic Response in Glioma.J Craniofac Surg202642412600PubTator, text miningPubMed
Application of single-cell RNA sequencing in preeclampsia.Front Glob Womens Health202642367612PubTator, text miningPubMed
Clocking immunity: circadian modulation of NK cells and emerging timing perspectives.Front Immunol202642327792PubTator, text miningPubMed
Cellular Heterogeneity in Erectile Dysfunction: An In-silico Analysis Revealing PER1, BHLHE40, NFIL3, and KLF10 as Circadian Rhythm Genes.Curr Med Chem202642304925PubTator, text miningPubMed
Hypoxia-responsive interaction between P-TEFb, BHLHE40, and Tim8-Tim13 regulates hypoxic gene transcription.Sci Adv202642160428PubTator, text miningPubMed
Identification of pyroptosis-related hub genes and immune cell infiltration in IgA nephropathy via bioinformatics analysis.Ren Fail202642135973PubTator, text miningPubMed
Atherosclerosis Profiling Reveals BHLHE40 as a Candidate Modulator of VSMC.Circ Res202642125810PubTator, text miningPubMed

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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