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Gene · 8564

Papers1,472

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A kynurenine immune-metabolic subtype of depression defined by childhood maltreatment and IDO2: Evidence from multi-omics profiling.Psychol Med202642803521PubTator, text miningPubMed
Biallelic Variants in KMO Cause a Novel Form of Congenital NAD Deficiency.medRxiv202642798303PubTator, text miningPubMed
Pharmacology-Informed Human Genetic Evaluation of Panax notoginseng Saponin-Related Candidate Genes for Functional Outcome After Ischemic Stroke Using Mendelian Randomization and Colocalization.Genes (Basel)202642793049PubTator, text miningPubMed
Kynurenine pathway dysregulation in attention-deficit hyperactivity disorder: Impact on N-methyl-D-aspartate receptors and phasic dopamine maturation.World J Clin Pediatr202642625969PubTator, text miningPubMed
The role of the kynurenine pathway in the pathogenesis of pain and affective disorders after traumatic brain injury.Brain Behav Immun Health202642577036PubTator, text miningPubMed
Integrative analysis of transcriptomics and metabolomics reveals mitochondria function genes and associated metabolite pathways in endometritis.Gene202642457000PubTator, text miningPubMed
Exploring the Microbiome-Kynurenine Axis in Mild Cognitive Impairment: From Gut to Brain.J Integr Neurosci202642411439PubTator, text miningPubMed
Domino Effect of the Kynurenine Pathway: Systemic Homeostasis, Metabolic Crosstalk, and Therapeutic Potential.Compr Physiol202642381240PubTator, text miningPubMed
Tryptophan Metabolism in Cardiometabolic Diseases: Focus on the Kynurenine Pathway.Int J Mol Sci202642352946PubTator, text miningPubMed
Kynurenine pathway at the crossroads of neurological and psychiatric disorders: Bridging metabolic dysregulation, therapeutic challenges, and emerging strategies.Prog Neuropsychopharmacol Biol Psychiatry202642315009PubTator, text miningPubMed
The kynurenine pathway: an immunometabolic bridge linking systemic inflammation to neuroaxonal vulnerability in multiple sclerosis.Front Cell Neurosci202642266250PubTator, text miningPubMed
The single nucleotide polymorphism rs1053230 modulates kynurenine 3-monooxygenase stability and is associated with cognitive and mood phenotypes.bioRxiv202642239117PubTator, text miningPubMed
The Metabolic Architecture of Glaucoma: A Unified Framework of Cofactor Failure and Kynurenine Dysregulation.Int J Mol Sci202642196293PubTator, text miningPubMed
Stage-Dependent Changes in Kynurenine Pathway Enzyme Expression Suggest Immune-Related Involvement in Bladder Cancer Progression.Int J Urol202642095396PubTator, text miningPubMed
Kynurenine Pathway, Nrf2 and NF-κB Cross-Regulation in the CNS: An Overview.Mol Neurobiol202641894093PubTator, text miningPubMed
Targeting the Kynurenine Pathway to Improve Mood Disorders.Curr Neuropharmacol202641863270PubTator, text miningPubMed
TDO2-Associated Tryptophan Metabolism Correlates with Impaired Tertiary Lymphoid Structure Maturation and Reduced B Cell Class Switching in Breast Cancer.Oncol Res202641799509PubTator, text miningPubMed
Fasting-Induced Changes in Serum Kynurenines Do Not Always Reflect Their Urinary Excretion.Nutrients202641754206PubTator, text miningPubMed
Modulation of the Kynurenine Pathway: A New Approach for Treating Neurodegeneration.Life (Basel)202641752903PubTator, text miningPubMed
Metabolic Mechanisms in Electroconvulsive Therapy for Schizophrenia: Role, Potential and Future Directions.Int J Mol Sci202641751887PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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