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Gene · 8570

KHSRP: KH-type splicing regulatory protein

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. KHSRP: KH-type splicing regulatory protein. Genes, record 8570. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8570

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Gene

Symbol
KHSRP
HGNC
Name
KH-type splicing regulatory protein
HGNC
NCBI Gene ID
8570
NCBI Gene
HGNC ID
HGNC:6316
HGNC
Ensembl
ENSG00000088247
NCBI Gene
Aliases
FBP2, FUBP2, KSRP, p75
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q92945Far upstream element-binding protein 27116Ensembl, GeneID, HGNC

Source UniProt

Patents32

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1450728Q92945Espacenet
EP 4650780 A22025-11-1911568Q92945Espacenet
EP 4641201 A22025-10-2912127Q92945Espacenet
JP 2025147176 A2025-10-0615205Q92945Espacenet
JP 2025517969 A2025-06-1212127Q92945Espacenet
JP 2025517970 A2025-06-1211568Q92945Espacenet
JP 2025028160 A2025-02-2815205Q92945Espacenet
KR 1020250010750 A2025-01-2115205Q92945Espacenet
JP 2024109657 A2024-08-1415044Q92945Espacenet
US 11446398 B22022-09-2043280Q92945Espacenet

1 to 10 of 32

See all 32 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants967

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleKHSRP papersNewest fiscal year
ZIAAG000511Post-transcriptional control of Proliferation, Stress Response & Carcinogenesis112025
R01DK057819Intestinal Mucosal Growth in Health and Surgical Diseases82025
P30CA008748Cancer Center Support Grant72025
P30CA016672Cancer Center Support Grant62025
ZIAAG000393Influence of Post-transcriptional Gene Regulation on Cell Senescence and Aging62025
ZIAES090080TTP and related proteins in the regulation of gene expression52025
I01BX000332Posttranscriptional Control of Gut Mucosal Defense and Homeostasis42025
R01NS089633Destabilization of axonal mRNAs by KHSRP complexes during axon regeneration42025
R01AR043369MITF from control of pigmentation to melanoma risk32025
R01DK018477Enhancer Connectomes in Regulation of Gene Expression32025

1 to 10 of 967Source NIH's project files

See all 967 nih grants

Papers1,446

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
An axon-intrinsic loop restricts nerve regeneration through axonal protein synthesis.Sci Adv202642647628PubTator, text miningPubMed
A novel small molecule inhibitor targeting KHSRP methylation suppresses colon cancer progression.Acta Pharm Sin B202642592425PubTator, text miningPubMed
Unraveling the Plasma Extracellular Vesicles Proteome: Predictors of Resistance in Immunotherapy of Advanced Melanoma.Int J Cancer202642437992PubTator, text miningPubMed
Divergent RNA structures support accurate splicing of the SF3B1-sensitive MAP3K7 intron.bioRxiv202642239186PubTator, text miningPubMed
KSRP-dependent immunogenic cell death induced by pyridazinone derivative IMB5036 drives antitumor immunity in neuroblastoma.FEBS Lett202642186376PubTator, text miningPubMed
Novel role of the lncRNA EPR as oncosuppressor in intestinal cancer.bioRxiv202642094402PubTator, text miningPubMed
Discovery of Biomarkers Related to Colorectal Cancer by Systematic Proteomics Analysis and Experimental Procedures.Iran J Med Sci202642039223PubTator, text miningPubMed
Integrative Multiomics Approaches Identify Biomarkers Associated With Progression From Arthralgia to Rheumatoid Arthritis.Arthritis Rheumatol202642010917PubTator, text miningPubMed
Trophoblast KHSRP deficiency induces DNA damage and apoptosis via TFPI2 in unexplained spontaneous miscarriage.Placenta202641932065PubTator, text miningPubMed
Long Non-Coding RNA Encoded by Infectious Bronchitis Virus Facilitates Viral Replication via Direct Interaction with G3BP2 and Expression Regulation of a Novel Host MicroRNA.Vet Sci202641893633PubTator, text miningPubMed

1 to 10 of 1,446

See all 1,446 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8570

GET https://conductscience.org/api/genes/v1/8570/patents?page=2