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RUNX1: RUNX family transcription factor 1

1 protein, 71 patents, 0 drugs, 0 trials, 7,917 NIH grants and 18,544 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolRUNX1HGNC
NameRUNX family transcription factor 1HGNC
NCBI Gene ID861NCBI Gene
HGNC IDHGNC:10471HGNC
EnsemblENSG00000159216NCBI Gene
AliasesAML1, AML1-EVI-1, AMLCR1, CBF2alpha, CBFA2, EVI-1, PEBP2A2, PEBP2aB, PEBP2alphaNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q01196Runt-related transcription factor 14535Ensembl, GeneID, HGNCUniProt

Patents 71

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4698657 A22026-02-25389Q01196Espacenet
EP 4650780 A22025-11-196566Q01196Espacenet
EP 4641201 A22025-10-296313Q01196Espacenet
JP 2025147176 A2025-10-0615588Q01196Espacenet
JP 2025517969 A2025-06-126313Q01196Espacenet
JP 2025517970 A2025-06-126566Q01196Espacenet
KR 1020250083381 A2025-06-101Q01196Espacenet
EP 4520828 A22025-03-121Q01196Espacenet
JP 2025028160 A2025-02-2815588Q01196Espacenet
EP 4504905 A22025-02-122Q01196Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 7917

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant2052,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)1992,025NIH's project files
P30CA008748Cancer Center Support Grant1922,025NIH's project files
P30CA016058Cancer Center Support Grant782,025NIH's project files
U10CA180886COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement542,025NIH's project files
U10CA180899Children's Oncology Group Statistics and Data Center492,025NIH's project files
P01CA066996Development of Novel Therapeutic Strategies in Human Leukemias412,025NIH's project files
P30CA091842Cancer Center Support Grant362,025NIH's project files
P30CA006973Regional Oncology Research Center342,025NIH's project files
U10CA180821Alliance for Clinical Trials in Oncology Operations Center - GY11 Funded Extension322,025NIH's project files

Papers 18544

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825269PubTator, text miningPubMed
42821569PubTator, text miningPubMed
42818321PubTator, text miningPubMed
42802443PubTator, text miningPubMed
42801378PubTator, text miningPubMed
42792602PubTator, text miningPubMed
42789377PubTator, text miningPubMed
42764945PubTator, text miningPubMed
42762611PubTator, text miningPubMed
42750117PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license