Gene · 8630
HSD17B6: hydroxysteroid 17-beta dehydrogenase 6
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. HSD17B6: hydroxysteroid 17-beta dehydrogenase 6. Genes, record 8630. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8630
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O14756 | 17-beta-hydroxysteroid dehydrogenase type 6 | 317 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents31
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 5203 | O14756 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5203 | O14756 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 39328 | O14756 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 39329 | O14756 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 39330 | O14756 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 39332 | O14756 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 39334 | O14756 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 142299 | O14756 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 142300 | O14756 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 142301 | O14756 | Espacenet |
1 to 10 of 31
See all 31 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,025
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | HSD17B6 papers | Newest fiscal year |
|---|---|---|---|
| P30ES013508 | Center of Excellence in Environmental Toxicology | 19 | 2025 |
| P01CA163227 | Androgen Receptor Action in Castration Resistant Prostate Cancer | 10 | 2025 |
| P50CA097186 | The Pacific Northwest Prostate Cancer SPORE | 10 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 5 | 2025 |
| R01EY009339 | Retinoids in Vision | 5 | 2025 |
| P30CA013148 | Comprehensive Cancer Center Support Grant | 4 | 2025 |
| U01DK061734 | Clinical Research on Nonalcoholic Fatty Liver Disease | 4 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,025Source NIH's project files
See all 1,025 nih grantsPapers1,491
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Effects of Fermentation Broth from the Biocontrol Fungus Diaporthe novem on Colletotrichum jiangxiense, the Causal Agent of Rhododendron Brown Spot, and Transcriptomic Analysis of the Pathogen. | Microorganisms | 2026 | 42514034 | PubTator, text mining | PubMed |
| Discovery of a borylated aza-arene chemotype as a direct HSF1 inhibitor targeting the DNA-binding domain. | Eur J Med Chem | 2026 | 42275931 | PubTator, text mining | PubMed |
| An integrated computational framework for hazard identification of emerging contaminants: a case study of 6PPD. | Environ Int | 2026 | 42225002 | PubTator, text mining | PubMed |
| Biomimetic Compartmentalization of Enzymes for Sustainable Coenzyme Recycling in Oxidative Photocatalysis. | Chembiochem | 2026 | 42178976 | PubTator, text mining | PubMed |
| Vitamin A as an essential nutrient: advances in biosynthesis. | Curr Opin Biotechnol | 2026 | 42161096 | PubTator, text mining | PubMed |
| An integrated bioinformatics analysis identifying ALOX15 as a novel pharmacological target for retinitis pigmentosa and diabetic retinopathy. | Medicine (Baltimore) | 2026 | 42152388 | PubTator, text mining | PubMed |
| The proteomics analysis of mitochondria-enriched fractions reveals alteration of key mitochondrial pathways in breast cancer cell lines. | J Proteomics | 2026 | 42025918 | PubTator, text mining | PubMed |
| Genetic evidence for causal relationship between general cognition and treatment resistance in schizophrenia. | Transl Psychiatry | 2026 | 41922311 | PubTator, text mining | PubMed |
| CSF1 regulates inflammation and apoptosis in intervertebral disc degeneration. | Sci Rep | 2026 | 41912624 | PubTator, text mining | PubMed |
| Unraveling the toxicological impact of Bisphenol A exposure on dermatomyositis: An integration of network toxicology and machine learning approaches. | PLoS One | 2026 | 41911226 | PubTator, text mining | PubMed |
1 to 10 of 1,491
See all 1,491 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8630
GET https://conductscience.org/api/genes/v1/8630/patents?page=2