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Gene · 8638

OASL: 2'-5'-oligoadenylate synthetase like

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. OASL: 2'-5'-oligoadenylate synthetase like. Genes, record 8638. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8638

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Gene

Symbol
OASL
HGNC
Name
2'-5'-oligoadenylate synthetase like
HGNC
NCBI Gene ID
8638
NCBI Gene
HGNC ID
HGNC:8090
HGNC
Ensembl
ENSG00000135114
NCBI Gene
Aliases
OASL1, OASLd, TRIP-14, TRIP14, p59 OASL, p59-OASL, p59OASL
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q156462'-5'-oligoadenylate synthase-like protein5142Ensembl, GeneID, HGNC

Source UniProt

Patents43

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026148146 A12026-07-0925Q15646Espacenet
JP 2026004568 A2026-01-1435698Q15646Espacenet
JP 2025062604 A2025-04-14145Q15646Espacenet
US 11884978 B22024-01-30639Q15646Espacenet
US 11446398 B22022-09-20145Q15646Espacenet
JP 2022524081 A2022-04-27103116Q15646Espacenet
US 11078247 B22021-08-037813Q15646Espacenet
US 10846371 B22020-11-2428Q15646Espacenet
EP 3504344 A12019-07-03828Q15646Espacenet
JP 2019054813 A2019-04-11216133Q15646Espacenet

1 to 10 of 43

See all 43 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,371

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleOASL papersNewest fiscal year
P30CA008748Cancer Center Support Grant102025
P30AG017265USC/UCLA Center on Biodemography and Population Health92025
U19AI135972SARS-CoV adaptations through a Systems Biology Lens (SYBIL)62025
P30CA046934University of Colorado Cancer Center Support Grant52025
P30CA047904Cancer Center Support Grant52025
R01AR071384Characterization of interferon kappa as a novel target in cutaneous lupus52025
P30AR075043University of Michigan Skin Biology and Diseases Resource-based Center42025
P51OD011092Support for National Primate Research Center42025
UL1TR001863Yale Clinical and Translational Science Award42025
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success42025

1 to 10 of 1,371Source NIH's project files

See all 1,371 nih grants

Papers1,763

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Advances in Cytosolic dsRNA Sensing of Viral Infections.Immunol Cell Biol202642802076PubTator, text miningPubMed
Transcriptomic signatures of mind-body transformations therapy in breast cancer: Downregulation of the interferon signaling pathway.Breast202642748847PubTator, text miningPubMed
Tape Strip Transcriptomics Reveal Nemolizumab Effects on Pruritus, Hyperplasia, Inflammation, and Extracellular Matrix Markers in Patients With Moderate-to-Severe Atopic Dermatitis.Allergy202642693785PubTator, text miningPubMed
ACSL5 drives pancreatic ductal adenocarcinoma by suppressing mitophagy and enhancing ferroptosis resistance via the JAK1-STAT1-OASL axis.Cancer Lett202642692137PubTator, text miningPubMed
IFIT3 silencing improves the sensitivity of gliomas to temozolomide by inactivating the PI3K/AKT signaling pathway.Behav Brain Res202642603632PubTator, text miningPubMed
Transcriptomic profiling reveals selective attenuation of interferon-associated inflammatory signaling and induction of metallothioneins by a zinc-containing oral rinse.Front Immunol202642577366PubTator, text miningPubMed
Non-Cytopathic Mammalian Orthoreovirus Infection Triggers Innate Immune Responses in Human Tonsil-Derived Mesenchymal Stem Cells: Implications for Cell Therapy Quality Control.Tissue Eng Regen Med202642467368PubTator, text miningPubMed
The Effect of Arginine Supplementation on Intestinal Antioxidant Capacity, Whole Blood Cell Count and Antiviral Immune Function of Piglets Infected with Porcine Epidemic Diarrhea Virus.Animals (Basel)202642450709PubTator, text miningPubMed
Genetic and molecular architecture of multiple sclerosis in gulf cooperation council populations: A scoping review and regional precision-neurology perspective.Mult Scler Relat Disord202642398277PubTator, text miningPubMed
Alpha-herpesvirus UL55 synergizes with ICP27 to suppress type I interferon production through conserved and host-adapted mechanisms.J Virol202642377976PubTator, text miningPubMed

1 to 10 of 1,763

See all 1,763 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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