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RUNX3: RUNX family transcription factor 3

1 protein, 68 patents, 0 drugs, 0 trials, 3,570 NIH grants and 6,116 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolRUNX3HGNC
NameRUNX family transcription factor 3HGNC
NCBI Gene ID864NCBI Gene
HGNC IDHGNC:10473HGNC
EnsemblENSG00000020633NCBI Gene
AliasesAML2, CBFA3, PEBP2A3, PEBP2aCNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q13761Runt-related transcription factor 34151Ensembl, GeneID, HGNCUniProt

Patents 68

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026505362 A2026-02-1355Q13761Espacenet
EP 4689133 A12026-02-1120Q13761Espacenet
EP 4661884 A22025-12-1755Q13761Espacenet
KR 1020250164814 A2025-11-2520Q13761Espacenet
JP 2025147176 A2025-10-0615591Q13761Espacenet
JP 2025521922 A2025-07-1067Q13761Espacenet
JP 2025028160 A2025-02-2815591Q13761Espacenet
WO 2025027060 A12025-02-06131Q13761Espacenet
KR 1020250010750 A2025-01-2115591Q13761Espacenet
JP 2024123008 A2024-09-108280Q13761Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3570

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant312,025NIH's project files
P30CA016672Cancer Center Support Grant292,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant162,025NIH's project files
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital152,025NIH's project files
U01CA167552Cancer Epidemiology Cohort in Male Health Professionals152,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award112,025NIH's project files
P30CA015704Cancer Center Support Grant102,025NIH's project files
ZIABC010671Genetic Analysis of T-cell Differentiation102,025NIH's project files
P30CA068485Cancer Center Support Grant92,025NIH's project files
P30DK058404Molecular and Cellular Basis for Digestive Diseases92,025NIH's project files

Papers 6116

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823180PubTator, text miningPubMed
42801631PubTator, text miningPubMed
42801446PubTator, text miningPubMed
42742904PubTator, text miningPubMed
42685004PubTator, text miningPubMed
42682391PubTator, text miningPubMed
42653451PubTator, text miningPubMed
42585234PubTator, text miningPubMed
42575785PubTator, text miningPubMed
42559704PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license