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AKR1C3: aldo-keto reductase family 1 member C3
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Gene · 8644

Papers2,828

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

61 to 80 of 2,828

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TitleJournalYearPMIDFound bySource
ARID3A Dysregulation Drives Colon Cancer Progression and Enhances Responsiveness to Aspirin.J Cell Mol Med202641605861PubTator, text miningPubMed
Effect of Glucoraphanin on the Abundance of Nrf2 Regulated Genes Within Circulating Small Extracellular Vesicles: A Pilot Dietary Intervention.Mol Nutr Food Res202641603376PubTator, text miningPubMed
A New Histology-Based Prognostic Index for Acute Lymphoblastic Leukemia: Preliminary Results of the "ALL Urayasu Classification".J Clin Med202641598705PubTator, text miningPubMed
Targeting AKR1B1 reprograms tumor-associated macrophages to enhance antitumor immunity.J Immunother Cancer202641592892PubTator, text miningPubMed
Multidimensional liquid biopsy in bladder cancer: advances in circulating tumor cells, circulating tumor DNA, exosomes, and metabolomics.Oncologist202641587949PubTator, text miningPubMed
AKR1C3 promotes aerobic glycolysis in hepatic stellate cells via the AKT/mTOR pathway to induce liver fibrosis.Cell Signal202641554490PubTator, text miningPubMed
Luteolin Attenuates Asthma Via Inhibiting ALOX15 Mediated Bronchial Epithelial Cell Ferroptosis.Inflammation202641547709PubTator, text miningPubMed
Androgen production in adrenocortical H295R cells is regulated by thyroid hormone T3 without reciprocal thyroid axis modulation in pediatric CAH.J Steroid Biochem Mol Biol202641544797PubTator, text miningPubMed
Integrative LC-MS/MS, Bioinformatics, and Molecular Dynamics Reveal Multitarget Antioxidant Mechanisms of Bushen Huoxue Decoction in Intervertebral Disc Degeneration.Biomed Chromatogr202641504373PubTator, text miningPubMed
Propolis from Heterotrigona apicalis (East Kalimantan) as a source of hepatoprotective and chemopreventive polyphenols: in vitro and in silico studies.3 Biotech202641502475PubTator, text miningPubMed
Multi-omics analysis of key lipid metabolism-related genes involved in the anti-hepatocellular carcinoma effect of dihydroartemisinin.Discov Oncol202641501557PubTator, text miningPubMed
Impact of AKR1C2 and AKR1C3 single-nucleotide polymorphism rs28571848 in adipose tissues of individuals with severe obesity.Am J Physiol Endocrinol Metab202641500516PubTator, text miningPubMed
An AKR1C3-activated kinase inhibitor prodrug.RSC Chem Biol202641488912PubTator, text miningPubMed
Integrating Single-Cell Sequencing, Machine Learning, and Molecular Docking to Elucidate the Molecular Network Linking Myocardial Infarction and DEHP Exposure.J Biochem Mol Toxicol202641459671PubTator, text miningPubMed
Arugula-derived isothiocyanates as novel agents for a potential regulator of AKR1B10 protein in breast cancer: an integrated transcriptomic and molecular docking approach.Naunyn Schmiedebergs Arch Pharmacol202641454951PubTator, text miningPubMed
Entinostat overcomes cisplatin resistance in bladder cancer by promoting H3K18la-mediated DHRS2 expression and nuclear translocation to suppress the AKR1C3-androgen axis.Drug Resist Updat202641401485PubTator, text miningPubMed
Casticin inhibits AKR1C3 and enhances abiraterone efficacy in castration-resistant prostate cancer.J Nat Med202641372579PubTator, text miningPubMed
Integrated multi-Omics and network toxicology elucidate the multi-target mechanisms of environmental hormones in driving hepatocellular carcinoma.Ecotoxicol Environ Saf202641371106PubTator, text miningPubMed
Interactome profiling reveals the LCMV nucleoprotein co-opts DDX helicases through conserved interfaces.Int J Biol Macromol202641360249PubTator, text miningPubMed
Exploring the roles of AKR1C1, AKR1C2, and AKR1C3 in the nervous system: Mechanisms and perspectives.Exp Neurol202641352453PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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