Gene · 8647
ABCB11: ATP binding cassette subfamily B member 11
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ABCB11: ATP binding cassette subfamily B member 11. Genes, record 8647. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8647
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O95342 | Bile salt export pump | 1,321 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents102
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4750895 A1 | 2026-06-03 | 7 | O95342 | Espacenet |
| JP 2026067851 A | 2026-04-21 | 81 | O95342 | Espacenet |
| US 12508234 B2 | 2025-12-30 | 3 | O95342 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 19668 | O95342 | Espacenet |
| JP 2025169942 A | 2025-11-14 | 865 | O95342 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 4081 | O95342 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 25479 | O95342 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 189 | O95342 | Espacenet |
| JP 2025525390 A | 2025-08-05 | 3650 | O95342 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 189 | O95342 | Espacenet |
1 to 10 of 102
See all 102 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,737
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ABCB11 papers | Newest fiscal year |
|---|---|---|---|
| P30DK034989 | Yale Liver Center | 28 | 2025 |
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 25 | 2025 |
| U01DK062453 | Colorado Center of Childhood Liver Disease ResearchNetwork | 19 | 2025 |
| R35GM122576 | Mechanisms of Altered Hepatic Transport: Impact on Drug Therapy | 16 | 2025 |
| P30DK026743 | UCSF Liver Center | 14 | 2025 |
| U01DK062497 | Clinical Center for Cholestatic Liver Disease in Children | 12 | 2025 |
| ZIABC005562 | Xenobiotic receptors | 12 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 10 | 2025 |
| P30ES005022 | Rutgers Center for Environmental Exposure and Disease (CEED) | 10 | 2025 |
| U01DK062481 | Advancing our Understanding of Rare Pediatric Liver Diseases | 10 | 2025 |
1 to 10 of 1,737Source NIH's project files
See all 1,737 nih grantsPapers3,310
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Mulberry leaf flavonoids alleviate type 2 diabetes by remodeling the gut microbiota-bile acid axis and activating FXR signaling. | J Ethnopharmacol | 2027 | 42503322 | PubTator, text mining | PubMed |
| Machine learning prediction of bile salt export pump inhibition with Boruta feature selection in imbalanced data. | Front Pharmacol | 2026 | 42781341 | PubTator, text mining | PubMed |
| Duodenal fluid analysis of 13 patients with progressive familial intrahepatic cholestasis type 2 from a single institution. | Medicine (Baltimore) | 2026 | 42760696 | PubTator, text mining | PubMed |
| Novel genetic variants and atypical phenotypes in pediatric progressive familial intrahepatic cholestasis. | Pediatr Res | 2026 | 42754724 | PubTator, text mining | PubMed |
| Genetic Spectrum of Cholestasis in Tunisia and Diagnostic Yield of Next-Generation Sequencing: Case Series of 70 Patients. | Clin Genet | 2026 | 42742065 | PubTator, text mining | PubMed |
| Mechanism of FXR signaling: from liver inflammation to hepatocellular carcinoma. | Biochem Biophys Rep | 2026 | 42699277 | PubTator, text mining | PubMed |
| Saxifraga umbellulata Attenuates Cholestatic Liver Injury and Modulates Farnesoid X Receptor-Related Bile Acid Homeostasis. | Pharmazie | 2026 | 42695244 | PubTator, text mining | PubMed |
| In Vitro Three-Dimensional Human Liver Model for Drug-Induced Liver and Bile Duct Injury Prediction. | Toxics | 2026 | 42647006 | PubTator, text mining | PubMed |
| Prediction of bile salt export pump inhibition using biomimetic chromatographic descriptors: Integrating membrane affinity and protein binding. | ADMET DMPK | 2026 | 42633372 | PubTator, text mining | PubMed |
| Progressive familial intrahepatic cholestasis disease burden and clinical approaches: a systematic review. | J Comp Eff Res | 2026 | 42616472 | PubTator, text mining | PubMed |
1 to 10 of 3,310
See all 3,310 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8647
GET https://conductscience.org/api/genes/v1/8647/patents?page=2