Gene · 8648
NCOA1: nuclear receptor coactivator 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NCOA1: nuclear receptor coactivator 1. Genes, record 8648. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8648
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q15788 | Nuclear receptor coactivator 1 | 1,441 | 303 | Ensembl, GeneID, HGNC |
Source UniProt
Patents57
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 56089 | Q15788 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 56092 | Q15788 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5348 | Q15788 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 4938 | Q15788 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15343 | Q15788 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 4938 | Q15788 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5348 | Q15788 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15343 | Q15788 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15343 | Q15788 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15182 | Q15788 | Espacenet |
1 to 10 of 57
See all 57 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,941
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NCOA1 papers | Newest fiscal year |
|---|---|---|---|
| R01HD007857 | Sex Hormone Receptor Component And The Cell Genome | 35 | 2025 |
| R01HD008188 | Reproductive Hormones - Biological and Molecular Actions | 32 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 29 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 19 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 17 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 12 | 2025 |
| R35GM118041 | Regulation of xenobiotic receptors PXR and CAR, and CYP3A: implications in drug disposition | 10 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 9 | 2025 |
| P30DK056338 | Texas Medical Center Digestive Diseases Center | 8 | 2025 |
| ZIABC011387 | Studies of gene fusions in rhabdomyosarcoma | 7 | 2025 |
1 to 10 of 1,941Source NIH's project files
See all 1,941 nih grantsPapers3,138
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Panaxytriol up-regulates CYP2B6 expression through PXR and CAR and their interactions with RXRα and SRC-1. | J Ethnopharmacol | 2026 | 42777982 | PubTator, text mining | PubMed |
| Whole-exome sequencing-centered genetic evaluation for early-onset obesity in Chinese children: a retrospective single-center cohort. | Transl Pediatr | 2026 | 42724349 | PubTator, text mining | PubMed |
| Targeting host lipogenesis with a diarylamide inhibitor disrupts SARS-CoV-2 replication. | iScience | 2026 | 42603033 | PubTator, text mining | PubMed |
| Uterine tumour resembling ovarian sex cord tumour (utrosct) associated with ctnnb1, pten and other gene mutations: Expanding the molecular landscape. | Virchows Arch | 2026 | 42593492 | PubTator, text mining | PubMed |
| Dual MDM2 and PPARG regulatory axes mediate the antiepileptic effects of Gouteng: An integration of bioinformatics, network pharmacology, machine learning, molecular docking, and MD simulations. | Neuropharmacology | 2026 | 42575349 | PubTator, text mining | PubMed |
| Integrated Clinicopathologic and Multiomic Profiling Reveals MEIS1-Rearranged Sarcoma as a Distinct Entity With 2 Prognostic Subgroups. | Mod Pathol | 2026 | 42471200 | PubTator, text mining | PubMed |
| Biphenotypic Sinonasal Sarcomas with Recurrent PAX3::FOXO6 Gene Fusion. | Head Neck Pathol | 2026 | 42446761 | PubTator, text mining | PubMed |
| Elevated ESR2 and BRCA1 gene expression in adenomyosis associated with endometrial cancer: a pilot study. | Gynecol Endocrinol | 2026 | 42329179 | PubTator, text mining | PubMed |
| Evaluation of the Ligand-Dependent Coactivator Recruitment of the Nuclear Receptor Pregnane X Receptor Using Its Three-Alanine Residues-Inserted Mutant. | Biol Pharm Bull | 2026 | 42324158 | PubTator, text mining | PubMed |
| Nonsteroidal Mineralocorticoid Receptor Antagonists in Heart Failure: Mechanistic Basis, Clinical Evidence, and Therapeutic Integration. | Drugs Drug Candidates | 2026 | 42305634 | PubTator, text mining | PubMed |
1 to 10 of 3,138
See all 3,138 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8648
GET https://conductscience.org/api/genes/v1/8648/patents?page=2