Gene · 865
CBFB: core-binding factor subunit beta
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CBFB: core-binding factor subunit beta. Genes, record 865. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/865
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13951 | Core-binding factor subunit beta | 182 | 20 | Ensembl, GeneID, HGNC |
Source UniProt
Patents33
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 42248 | Q13951 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3444 | Q13951 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3027 | Q13951 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 14818 | Q13951 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3027 | Q13951 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3444 | Q13951 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 25876 | Q13951 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 14818 | Q13951 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 14818 | Q13951 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 25876 | Q13951 | Espacenet |
1 to 10 of 33
See all 33 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,808
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CBFB papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 57 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 38 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 32 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 24 | 2025 |
| ZIAHG000030 | Mechanistic and translational studies of CBF leukemia | 23 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 11 | 2025 |
| U10CA180821 | Alliance for Clinical Trials in Oncology Operations Center - GY11 Funded Extension | 10 | 2025 |
| U10CA180886 | COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement | 10 | 2025 |
| U10CA180882 | Alliance Statistics and Data Management Center | 9 | 2025 |
| U10CA180899 | Children's Oncology Group Statistics and Data Center | 9 | 2025 |
1 to 10 of 1,808Source NIH's project files
See all 1,808 nih grantsPapers3,690
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A chromatin-informed transcriptional regulatory framework to stratify patients and guide therapy selection in triple-negative breast cancer. | Nat Commun | 2026 | 42749733 | PubTator, text mining | PubMed |
| T-Cell Leukemia Cell Line Harboring Previously Undescribed CBFB::MYL11 Fusion Exhibits a Genome Profile Implicating Cytoskeletal Abnormality. | Acta Haematol | 2026 | 42726671 | PubTator, text mining | PubMed |
| ReprogRAM nanoplatform for direct conversion of fibroblasts to osteoblasts for bone regeneration. | J Control Release | 2026 | 42617699 | PubTator, text mining | PubMed |
| Structural Basis of Intermolecular Interactions Between APOBEC3 and HIV-1 Vif. | Viruses | 2026 | 42515639 | PubTator, text mining | PubMed |
| Core binding factor β preserves early chondrogenic identity and prevents hypertrophic transition in cartilage organoids formation. | Cell Biosci | 2026 | 42421090 | PubTator, text mining | PubMed |
| CBFβ-SMMHC in inv(16) AML: Fusion biology, RUNX1 dysregulation, and therapeutic targeting of a leukemogenic protein-protein interaction. | Pathol Res Pract | 2026 | 42391722 | PubTator, text mining | PubMed |
| Hypoxia induced DNMT3B and SHP2 signaling promoted HCC via suppressing P53 and MYH11 protein expression. | Front Oncol | 2026 | 42376659 | PubTator, text mining | PubMed |
| The structural mechanism of HIV-2 Vif antagonism of human APOBEC3H. | Nat Commun | 2026 | 42373647 | PubTator, text mining | PubMed |
| Extracellular vesicle cargo dynamics in the bone marrow microenvironment: from hematopoietic homeostasis to malignant transformation. | Extracell Vesicle | 2026 | 42344609 | PubTator, text mining | PubMed |
| Protein-based nanocarrier delivering kartogenin derivative to cartilage matrix for intra-articular treatment of osteoarthritis. | J Drug Deliv Sci Technol | 2026 | 42305633 | PubTator, text mining | PubMed |
1 to 10 of 3,690
See all 3,690 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/865
GET https://conductscience.org/api/genes/v1/865/patents?page=2