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SOCS1: suppressor of cytokine signaling 1

1 protein, 107 patents, 0 drugs, 0 trials, 4,150 NIH grants and 8,326 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSOCS1HGNC
Namesuppressor of cytokine signaling 1HGNC
NCBI Gene ID8651NCBI Gene
HGNC IDHGNC:19383HGNC
EnsemblENSG00000185338NCBI Gene
AliasesAISIMD, CIS1, CISH1, Cish1, JAB, SOCS-1, SSI-1, SSI1, TIP-3, TIP3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O15524Suppressor of cytokine signaling 12110Ensembl, GeneID, HGNCUniProt

Patents 107

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026106462 A2026-06-291O15524Espacenet
EP 4694917 A12026-02-18655O15524Espacenet
WO 2025244125 A2025-11-2725O15524Espacenet
EP 4641201 A22025-10-295510O15524Espacenet
EP 4641202 A22025-10-295018O15524Espacenet
WO 2025217136 A22025-10-16239O15524Espacenet
JP 2025147176 A2025-10-0616609O15524Espacenet
WO 2025163107 A12025-08-072O15524Espacenet
JP 2025517969 A2025-06-125510O15524Espacenet
JP 2025028160 A2025-02-2816609O15524Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4150

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant292,025NIH's project files
P30CA016672Cancer Center Support Grant282,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award162,025NIH's project files
U01CA167552Cancer Epidemiology Cohort in Male Health Professionals152,025NIH's project files
P30CA016058Cancer Center Support Grant122,025NIH's project files
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital112,025NIH's project files
R01AI100874The natural killer cell response against mouse cytomegalovirus infection112,025NIH's project files
P30CA015704Cancer Center Support Grant92,025NIH's project files
ZIAEY000372Mechanisms of immune homeostasis and regulation of intraocular inflammation92,025NIH's project files
ZIASC000550Lymphoma Disease Discovery and Definition92,025NIH's project files

Papers 8326

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825374PubTator, text miningPubMed
42822323PubTator, text miningPubMed
42804630PubTator, text miningPubMed
42745635PubTator, text miningPubMed
42745343PubTator, text miningPubMed
42737820PubTator, text miningPubMed
42736823PubTator, text miningPubMed
42661118PubTator, text miningPubMed
42660682PubTator, text miningPubMed
42640698PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license