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Gene · 866

SERPINA6: serpin family A member 6

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SERPINA6: serpin family A member 6. Genes, record 866. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/866

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Gene

Symbol
SERPINA6
HGNC
Name
serpin family A member 6
HGNC
NCBI Gene ID
866
NCBI Gene
HGNC ID
HGNC:1540
HGNC
Ensembl
ENSG00000170099
NCBI Gene
Aliases
CBG
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P08185Corticosteroid-binding globulin4055Ensembl, GeneID, HGNC

Source UniProt

Patents58

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1463187P08185Espacenet
JP 2026500221 A2026-01-0622P08185Espacenet
EP 4650780 A22025-11-196766P08185Espacenet
JP 2025147176 A2025-10-0612065P08185Espacenet
JP 2025529142 A2025-09-047681P08185Espacenet
US 12371689 B22025-07-297681P08185Espacenet
JP 2025517970 A2025-06-126766P08185Espacenet
JP 2025028160 A2025-02-2812065P08185Espacenet
KR 1020250010750 A2025-01-2112065P08185Espacenet
JP 2024109657 A2024-08-1412072P08185Espacenet

1 to 10 of 58

See all 58 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants905

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSERPINA6 papersNewest fiscal year
ZIAES090057Glucocorticoid Hormone Action72025
P30CA008748Cancer Center Support Grant32025
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)32025
ZIADK075122The differential diagnosis and treatment of Cushing's syndrome32025
P30AI050409Center for AIDS Research at Emory University22025
P30DK048520Colorado Nutrition Obesity Research Center22025
P30ES023515Mount Sinai Center for Health and Environment Across the LifeSpan (HEALS)22025
P50AA017823Developmental Exposure Alcohol Research Center22025
R01AA012207Family Health Patterns: A Study Across Generations22025
R01DK015070Thyroid Physiology Studies of Inherited Disorders22025

1 to 10 of 905Source NIH's project files

See all 905 nih grants

Papers2,321

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Diagnostic Accuracy Study of Morning Salivary Cortisone for Screening Adrenal Insufficiency in a Real-World Cohort.J Clin Endocrinol Metab202642806822PubTator, text miningPubMed
Modeling cortisol and cortisone binding to corticosteroid-binding globulin and albumin based on clinical protein binding data.Drug Metab Dispos202642541914PubTator, text miningPubMed
Prospective evaluation of the effect of stopping estrogen-containing contraceptives on serum CBG and cortisol levels.J Clin Endocrinol Metab202642339516PubTator, text miningPubMed
The roles, mechanisms, and therapeutic implications of glucocorticoids in glucose and lipid metabolism.Mil Med Res202642199346PubTator, text miningPubMed
Longitudinal Plasma Proteomics Reveals an Immuno-thrombotic Signature That Predicts Radiation Pneumonitis in Lung Cancer.Int J Radiat Oncol Biol Phys202642176864PubTator, text miningPubMed
The dynamic adrenal response of children to cardiac surgery and cardiac catheterization.J Clin Endocrinol Metab202642128807PubTator, text miningPubMed
Corticosterone as a Physiological Biomarker: Decoding the Environment-Cort-Energy Paradigm.Ecol Evol202642063662PubTator, text miningPubMed
Kinetics of cortisol and cortisone binding to corticosteroid binding globulin and albumin in vivo.bioRxiv202642039475PubTator, text miningPubMed
ELISA-based validation of differentially expressed Fibrinogen, S100A9, SERPINA3 and SERPINA6 proteins in Polycystic Ovary Syndrome (PCOS).Steroids202642034305PubTator, text miningPubMed
TS3 Asn347 corticosteroid-binding globulin (CBG) glycoform deficiency is associated with mortality in human septic shock.J Endocr Soc202641994485PubTator, text miningPubMed

1 to 10 of 2,321

See all 2,321 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/866

GET https://conductscience.org/api/genes/v1/866/patents?page=2