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CBL: Cbl proto-oncogene

1 protein, 37 patents, 0 drugs, 0 trials, 3,976 NIH grants and 7,624 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCBLHGNC
NameCbl proto-oncogeneHGNC
NCBI Gene ID867NCBI Gene
HGNC IDHGNC:1541HGNC
EnsemblENSG00000110395NCBI Gene
AliasesC-CBL, CBL2, FRA11B, NSLL, RNF55, c-CblNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P22681E3 ubiquitin-protein ligase CBL90634Ensembl, GeneID, HGNCUniProt

Patents 37

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12539325 B22026-02-0357P22681Espacenet
JP 2026004568 A2026-01-1440136P22681Espacenet
EP 4650780 A22025-11-192291P22681Espacenet
EP 4641201 A22025-10-291857P22681Espacenet
JP 2025517969 A2025-06-121857P22681Espacenet
JP 2025517970 A2025-06-122291P22681Espacenet
US 12133879 B22024-11-0557P22681Espacenet
US 11872193 B22024-01-1657P22681Espacenet
EP 4223770 A22023-08-0992P22681Espacenet
US 11446398 B22022-09-2012661P22681Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3976

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant762,025NIH's project files
P30CA016672Cancer Center Support Grant612,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)292,025NIH's project files
P30CA016058Cancer Center Support Grant152,025NIH's project files
ZIABC010304Biochemical Basis of T Cell Activation152,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant142,025NIH's project files
T32CA009476Cancer Biology Training Program132,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award132,025NIH's project files
ZIABC010977Cbl Proteins as Regulators of Tyrosine Kinase Signaling132,025NIH's project files
ZIASC007263Activating Cell Death Pathways in Breast Cancer Cells132,025NIH's project files

Papers 7624

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42808596PubTator, text miningPubMed
42771522PubTator, text miningPubMed
42769548PubTator, text miningPubMed
42768151PubTator, text miningPubMed
42758873PubTator, text miningPubMed
42724212PubTator, text miningPubMed
42686514PubTator, text miningPubMed
42662874PubTator, text miningPubMed
42586899PubTator, text miningPubMed
42568796PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license