Gene · 8671
SLC4A4: solute carrier family 4 member 4
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SLC4A4: solute carrier family 4 member 4. Genes, record 8671. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8671
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9Y6R1 | Electrogenic sodium bicarbonate cotransporter 1 | 1,079 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents33
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026090543 A | 2026-06-02 | 819 | Q9Y6R1 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 64604 | Q9Y6R1 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2361 | Q9Y6R1 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 277 | Q9Y6R1 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1935 | Q9Y6R1 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 4254 | Q9Y6R1 | Espacenet |
| WO 2025169993 A | 2025-08-14 | 8 | Q9Y6R1 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 4254 | Q9Y6R1 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 277 | Q9Y6R1 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1935 | Q9Y6R1 | Espacenet |
1 to 10 of 33
See all 33 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,054
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SLC4A4 papers | Newest fiscal year |
|---|---|---|---|
| ZIADE000735 | Ca2+ signaling and HCO3- secretion by exocrine glands | 7 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 4 | 2025 |
| P30DK084567 | Mayo Center for Cell Signaling in Gastroenterology | 4 | 2025 |
| P30ES009089 | Center for Environmental Health in Northern Manhattan | 4 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 3 | 2025 |
| P30DK034987 | Center for Gastrointestinal Biology and Disease | 3 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 3 | 2025 |
| P30EY003176 | UC Berkeley Vision Science CORE | 3 | 2025 |
| P50HD103555 | Baylor College of Medicine Intellectual and Developmental Disabilities Research Center | 3 | 2025 |
| R01DK057061 | Calcium Dynamics in Interstitial Cells of Cajal | 3 | 2025 |
1 to 10 of 1,054Source NIH's project files
See all 1,054 nih grantsPapers1,389
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Blood-Derived DNA Methylation Biomarkers Predict Diabetic Kidney Disease and Map to Epigenomic Remodeling in Renal Cells. | Diabetes | 2026 | 42821458 | PubTator, text mining | PubMed |
| Stroke drives glioma progression through the emergence of tumor-associated astrocytes with reduced Ca2+ activity. | Nat Cancer | 2026 | 42791388 | PubTator, text mining | PubMed |
| Mechanistic insights into Na+-dependent HCO3- transport by NBCn2 (SLC4A10). | Structure | 2026 | 42641598 | PubTator, text mining | PubMed |
| Lactylation of EIF4A3 mediates sustained circPTK2 biogenesis to drive prostate cancer metastasis. | Cancer Lett | 2026 | 42595075 | PubTator, text mining | PubMed |
| Sex differences in renal acid-base regulation. | Curr Opin Nephrol Hypertens | 2026 | 42396848 | PubTator, text mining | PubMed |
| Gill ionocytes of the Lake Magadi tilapia (Oreochromis Alcolapia grahami), an extremophilic teleost native to a highly alkaline environment. | Cell Tissue Res | 2026 | 42334627 | PubTator, text mining | PubMed |
| Uncovering genes driving developmental stage progression in prostate cancer through spatial transcriptomics. | Genes Dis | 2026 | 42290662 | PubTator, text mining | PubMed |
| Therapeutic Potential of Allomyrinasin in Oral Squamous Cell Carcinoma via Decreased NBC Activity. | Pharmaceutics | 2026 | 42198315 | PubTator, text mining | PubMed |
| Membrane-associated Rhes-Slc4a7 complex orchestrates tunneling nanotube formation and mutant Huntingtin spread. | Sci Adv | 2026 | 41861004 | PubTator, text mining | PubMed |
| A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema. | Ann Clin Transl Neurol | 2026 | 41841191 | PubTator, text mining | PubMed |
1 to 10 of 1,389
See all 1,389 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8671
GET https://conductscience.org/api/genes/v1/8671/patents?page=2