Gene · 8685
MARCO: macrophage receptor with collagenous structure
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MARCO: macrophage receptor with collagenous structure. Genes, record 8685. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8685
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UEW3 | Macrophage receptor MARCO | 520 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents178
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 52201 | Q9UEW3 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 4808 | Q9UEW3 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2550 | Q9UEW3 | Espacenet |
| US 12378311 B2 | 2025-08-05 | 384 | Q9UEW3 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2550 | Q9UEW3 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 4808 | Q9UEW3 | Espacenet |
| US 12240899 B2 | 2025-03-04 | 154 | Q9UEW3 | Espacenet |
| WO 2024215782 A1 | 2024-10-17 | 154 | Q9UEW3 | Espacenet |
| WO 2024215787 A1 | 2024-10-17 | 154 | Q9UEW3 | Espacenet |
| JP 2023549555 A | 2023-11-27 | 436 | Q9UEW3 | Espacenet |
1 to 10 of 178
See all 178 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,279
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MARCO papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 11 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 4 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 4 | 2025 |
| R01AI148144 | Clearance of Blood-Borne Arboviruses | 4 | 2025 |
| T32AI007413 | Research Training in Experimental Immunology | 4 | 2025 |
| U19AI135964 | Successful Clinical Response In Pneumonia Therapy (SCRIPT) Systems Biology Center | 4 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 3 | 2025 |
| R01AR046713 | Cytokine regulation of RA synoviocyte phenotype | 3 | 2025 |
| T32AI007405 | Training Program in Immunology | 3 | 2025 |
1 to 10 of 1,279Source NIH's project files
See all 1,279 nih grantsPapers1,530
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Gene Expression Signatures Associated with Pterygium Recurrence. | J Clin Med | 2026 | 42796028 | PubTator, text mining | PubMed |
| Integrated multi-omics analysis indicates MARCO and ZBTB20 as candidate biomarkers in rheumatoid arthritis and tuberculosis. | Front Immunol | 2026 | 42741539 | PubTator, text mining | PubMed |
| The light side of mast cell degranulation: delivering macrophage repair through molecular condensates. | J Leukoc Biol | 2026 | 42740557 | PubTator, text mining | PubMed |
| A serpin-myeloid axis in pancreatic cancer heterogeneity and immune evasion. | Nature | 2026 | 42717081 | PubTator, text mining | PubMed |
| Spatial transcriptomics and histopathological analyses reveal potential biomarkers and immune features linked to recurrence in head and neck cancer. | Front Immunol | 2026 | 42643341 | PubTator, text mining | PubMed |
| MARCO is associated with radiosensitivity in lung cancer through modulation of Hippo signaling. | Immunobiology | 2026 | 42628137 | PubTator, text mining | PubMed |
| Correction for Yang et al., Superenhancer drives a tumor-specific splicing variant of MARCO to promote triple-negative breast cancer progression. | Proc Natl Acad Sci U S A | 2026 | 42607226 | PubTator, text mining | PubMed |
| Cancer immunotherapy targeting murine myeloid cells requires endosomal pattern recognition. | Nat Commun | 2026 | 42509237 | PubTator, text mining | PubMed |
| Integrated spatially guided transcriptomics and multiplex imaging identify a high-risk CD163+/CD11c-subgroup in diffuse large B-cell lymphoma. | Haematologica | 2026 | 42489074 | PubTator, text mining | PubMed |
| A nerve and mast cell sentinel system releases extracellular condensates to induce macrophage repair. | J Exp Med | 2026 | 42484560 | PubTator, text mining | PubMed |
1 to 10 of 1,530
See all 1,530 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8685
GET https://conductscience.org/api/genes/v1/8685/patents?page=2