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Gene · 8685

MARCO: macrophage receptor with collagenous structure

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MARCO: macrophage receptor with collagenous structure. Genes, record 8685. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8685

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Gene

Symbol
MARCO
HGNC
Name
macrophage receptor with collagenous structure
HGNC
NCBI Gene ID
8685
NCBI Gene
HGNC ID
HGNC:6895
HGNC
Ensembl
ENSG00000019169
NCBI Gene
Aliases
SCARA2, SR-A6
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UEW3Macrophage receptor MARCO5200Ensembl, GeneID, HGNC

Source UniProt

Patents178

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1452201Q9UEW3Espacenet
EP 4641201 A22025-10-294808Q9UEW3Espacenet
JP 2025529142 A2025-09-042550Q9UEW3Espacenet
US 12378311 B22025-08-05384Q9UEW3Espacenet
US 12371689 B22025-07-292550Q9UEW3Espacenet
JP 2025517969 A2025-06-124808Q9UEW3Espacenet
US 12240899 B22025-03-04154Q9UEW3Espacenet
WO 2024215782 A12024-10-17154Q9UEW3Espacenet
WO 2024215787 A12024-10-17154Q9UEW3Espacenet
JP 2023549555 A2023-11-27436Q9UEW3Espacenet

1 to 10 of 178

See all 178 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,279

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMARCO papersNewest fiscal year
P30CA008748Cancer Center Support Grant112025
P30CA016672Cancer Center Support Grant92025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202842025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center42025
R01AI148144Clearance of Blood-Borne Arboviruses42025
T32AI007413Research Training in Experimental Immunology42025
U19AI135964Successful Clinical Response In Pneumonia Therapy (SCRIPT) Systems Biology Center42025
P30CA015704Cancer Center Support Grant32025
R01AR046713Cytokine regulation of RA synoviocyte phenotype32025
T32AI007405Training Program in Immunology32025

1 to 10 of 1,279Source NIH's project files

See all 1,279 nih grants

Papers1,530

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Gene Expression Signatures Associated with Pterygium Recurrence.J Clin Med202642796028PubTator, text miningPubMed
Integrated multi-omics analysis indicates MARCO and ZBTB20 as candidate biomarkers in rheumatoid arthritis and tuberculosis.Front Immunol202642741539PubTator, text miningPubMed
The light side of mast cell degranulation: delivering macrophage repair through molecular condensates.J Leukoc Biol202642740557PubTator, text miningPubMed
A serpin-myeloid axis in pancreatic cancer heterogeneity and immune evasion.Nature202642717081PubTator, text miningPubMed
Spatial transcriptomics and histopathological analyses reveal potential biomarkers and immune features linked to recurrence in head and neck cancer.Front Immunol202642643341PubTator, text miningPubMed
MARCO is associated with radiosensitivity in lung cancer through modulation of Hippo signaling.Immunobiology202642628137PubTator, text miningPubMed
Correction for Yang et al., Superenhancer drives a tumor-specific splicing variant of MARCO to promote triple-negative breast cancer progression.Proc Natl Acad Sci U S A202642607226PubTator, text miningPubMed
Cancer immunotherapy targeting murine myeloid cells requires endosomal pattern recognition.Nat Commun202642509237PubTator, text miningPubMed
Integrated spatially guided transcriptomics and multiplex imaging identify a high-risk CD163+/CD11c-subgroup in diffuse large B-cell lymphoma.Haematologica202642489074PubTator, text miningPubMed
A nerve and mast cell sentinel system releases extracellular condensates to induce macrophage repair.J Exp Med202642484560PubTator, text miningPubMed

1 to 10 of 1,530

See all 1,530 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8685

GET https://conductscience.org/api/genes/v1/8685/patents?page=2