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ACTN1: actinin alpha 1

1 protein, 74 patents, 0 drugs, 0 trials, 5,138 NIH grants and 7,594 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolACTN1HGNC
Nameactinin alpha 1HGNC
NCBI Gene ID87NCBI Gene
HGNC IDHGNC:163HGNC
EnsemblENSG00000072110NCBI Gene
AliasesBDPLT15NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P12814Alpha-actinin-18924Ensembl, GeneID, HGNCUniProt

Patents 74

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-19181P12814Espacenet
EP 4641201 A22025-10-29150P12814Espacenet
JP 2025517969 A2025-06-12150P12814Espacenet
JP 2025517970 A2025-06-12181P12814Espacenet
JP 2025062604 A2025-04-141518P12814Espacenet
JP 2025038035 A2025-03-184355P12814Espacenet
US 12134655 B22024-11-054355P12814Espacenet
JP 2024123008 A2024-09-104742P12814Espacenet
US 11446398 B22022-09-201518P12814Espacenet
JP 2022530667 A2022-06-304355P12814Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5138

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01HL113006Human Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling242,025NIH's project files
P30CA016672Cancer Center Support Grant152,025NIH's project files
P30CA008748Cancer Center Support Grant132,025NIH's project files
R01HL076485Engineering Vascularized Cardiac Muscle132,025NIH's project files
R01HL130020Elucidating Mechanism of Cardiac Fibrosis with Cell Village of Pooled Human iPSCs132,025NIH's project files
P30DK058404Molecular and Cellular Basis for Digestive Diseases112,025NIH's project files
R01GM066817The Biochemical Basis for the Mechanics of Cytokinesis112,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program92,025NIH's project files
R01HL131017Myocardial remuscularization by cardiac patch delivery of epicardial FSTL1 and CCND2 overexpressing cardiomyocytes82,025NIH's project files
P30CA006973Regional Oncology Research Center72,025NIH's project files

Papers 7594

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42817999PubTator, text miningPubMed
42814603PubTator, text miningPubMed
42751622PubTator, text miningPubMed
42729422PubTator, text miningPubMed
42714311PubTator, text miningPubMed
42650812PubTator, text miningPubMed
42644246PubTator, text miningPubMed
42637409PubTator, text miningPubMed
42635255PubTator, text miningPubMed
42620598PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license