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TNFRSF25: TNF receptor superfamily member 25

1 protein, 164 patents, 0 drugs, 0 trials, 2,571 NIH grants and 5,848 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTNFRSF25HGNC
NameTNF receptor superfamily member 25HGNC
NCBI Gene ID8718NCBI Gene
HGNC IDHGNC:11910HGNC
EnsemblENSG00000215788NCBI Gene
AliasesAPO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LRNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q93038Tumor necrosis factor receptor superfamily member 254173Ensembl, GeneID, HGNCUniProt

Patents 164

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026512312 A2026-04-1532Q93038Espacenet
WO 2026019692 A22026-01-2225Q93038Espacenet
KR 1020250167626 A2025-12-0132Q93038Espacenet
EP 4650780 A22025-11-197362Q93038Espacenet
EP 4628503 A22025-10-0827Q93038Espacenet
JP 2025147176 A2025-10-0613599Q93038Espacenet
JP 2025147176 A2025-10-0616506Q93038Espacenet
JP 2025147176 A2025-10-0616617Q93038Espacenet
JP 2025529142 A2025-09-045010Q93038Espacenet
JP 2025529142 A2025-09-047942Q93038Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2571

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01DK032083Multiple Autoantigens, Multiple Epitopes of Type 1 Diabetes502,025NIH's project files
P30DK017047Diabetes Research Center252,025NIH's project files
P30CA008748Cancer Center Support Grant162,025NIH's project files
P30DK116073University of Colorado Anschutz Medical Campus DRC132,025NIH's project files
P01AI042288Immune Function and the Progression to Type 1 Diabetes122,025NIH's project files
U01DK103282Type 1 Diabetes TrialNet Clinical Network Hub122,025NIH's project files
P30DK048520Colorado Nutrition Obesity Research Center112,025NIH's project files
R01AI024717Genetic Linkage in Lupus102,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award102,025NIH's project files
P01CA018029Adult Leukemia Research Center92,025NIH's project files

Papers 5848

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42633936PubTator, text miningPubMed
42522260PubTator, text miningPubMed
42478648PubTator, text miningPubMed
42364076PubTator, text miningPubMed
42361136PubTator, text miningPubMed
42356043PubTator, text miningPubMed
42308012PubTator, text miningPubMed
42251338PubTator, text miningPubMed
42166713PubTator, text miningPubMed
42106953PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license