Gene · 8726
EED: embryonic ectoderm development
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EED: embryonic ectoderm development. Genes, record 8726. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8726
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O75530 | Polycomb protein EED | 441 | 81 | Ensembl, GeneID, HGNC |
Source UniProt
Patents36
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4828973 A2 | 2026-10-28 | 54 | O75530 | Espacenet |
| EP 4805378 A1 | 2026-09-16 | 566 | O75530 | Espacenet |
| JP 2026523341 A | 2026-07-14 | 1025 | O75530 | Espacenet |
| EP 4771137 A1 | 2026-07-08 | 563 | O75530 | Espacenet |
| EP 4771157 A1 | 2026-07-08 | 563 | O75530 | Espacenet |
| US 12649003 B2 | 2026-06-09 | 1025 | O75530 | Espacenet |
| JP 2026510339 A | 2026-04-02 | 563 | O75530 | Espacenet |
| EP 4713451 A2 | 2026-03-25 | 563 | O75530 | Espacenet |
| EP 4713452 A2 | 2026-03-25 | 563 | O75530 | Espacenet |
| US 12558437 B2 | 2026-02-24 | 1025 | O75530 | Espacenet |
1 to 10 of 36
See all 36 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,528
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EED papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 41 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 24 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 13 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 11 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 11 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 10 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 9 | 2025 |
| R01CA097098 | Targeting the MUC1-C Oncoprotein in Triple-Negative Breast Cancer | 8 | 2025 |
| R01CA199652 | Repression via Facultative Heterochromatin | 8 | 2025 |
| P30CA023168 | Cancer Center Support Grant | 7 | 2025 |
1 to 10 of 2,528Source NIH's project files
See all 2,528 nih grantsPapers3,114
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Interrupted surveillance and delayed genetic evaluation in neurofibromatosis type 1 associated with advanced malignant peripheral nerve sheath tumor and breast cancer: A case report. | Int Cancer Conf J | 2026 | 42781021 | PubTator, text mining | PubMed |
| PRC2 loss in MPNST is accompanied by SWI/SNF complex rewiring and sensitization to SMARCA2/4 and BET inhibition in vivo. | Mol Cell Proteomics | 2026 | 42759702 | PubTator, text mining | PubMed |
| Polycomb scaffolding subunit EED supports the SCLC neuroendocrine identity and EGFR-mutant LUAD-to-SCLC transformation. | J Clin Invest | 2026 | 42611544 | PubTator, text mining | PubMed |
| Case Report: Recurrent malignant phyllodes tumor with malignant peripheral nerve sheath tumor-like differentiation and loss of H3K27me3/RB1 expression. | Front Oncol | 2026 | 42582074 | PubTator, text mining | PubMed |
| Oncogenic Ras drives EED degradation and PRC2 dysfunction to promote aggressive squamous cell carcinoma. | Nat Commun | 2026 | 42443217 | PubTator, text mining | PubMed |
| Polycomb protein embryonic ectoderm development supports UV-induced effector regulatory T-cell responses in cutaneous inflammation. | J Invest Dermatol | 2026 | 42425363 | PubTator, text mining | PubMed |
| Genome wide association study meta-analysis of neuropathologic lesions of Alzheimer's disease and related dementias in a multi-site autopsy cohort. | PLoS Genet | 2026 | 42371968 | PubTator, text mining | PubMed |
| Identification and Prognostic Analysis of Immune-Related Genes Co-Regulated by Key Histone Modifications in Breast Cancer. | Curr Issues Mol Biol | 2026 | 42353587 | PubTator, text mining | PubMed |
| Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2-Selective Small Molecule Inhibitor. | Adv Sci (Weinh) | 2026 | 42314051 | PubTator, text mining | PubMed |
| EZH2 Serine 21 Phosphorylation Restrains Compact-State PRC2 Activation and H3K27me3 Propagation. | bioRxiv | 2026 | 42282706 | PubTator, text mining | PubMed |
1 to 10 of 3,114
See all 3,114 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8726
GET https://conductscience.org/api/genes/v1/8726/patents?page=2