Gene · 8741
TNFSF13: TNF superfamily member 13
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TNFSF13: TNF superfamily member 13. Genes, record 8741. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8741
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O75888 | Tumor necrosis factor ligand superfamily member 13 | 250 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents290
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026094457 A | 2026-06-09 | 85 | O75888 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6815 | O75888 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 985 | O75888 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 6617 | O75888 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 16618 | O75888 | Espacenet |
| JP 2025138725 A | 2025-09-25 | 2211 | O75888 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 985 | O75888 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 6617 | O75888 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 6815 | O75888 | Espacenet |
| JP 2025514142 A | 2025-05-02 | 85 | O75888 | Espacenet |
1 to 10 of 290
See all 290 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials23
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07020923 | ATACICEPT | PHASE2 | ClinicalTrials.gov | |
| NCT06983028 | ATACICEPT | PHASE2 | ClinicalTrials.gov | |
| NCT06928142 | SIBEPRENLIMAB | PHASE2 | ClinicalTrials.gov | |
| NCT06740526 | SIBEPRENLIMAB | PHASE2 | ClinicalTrials.gov | |
| NCT06674577 | ATACICEPT | PHASE2 | ClinicalTrials.gov | |
| NCT05609812 | ATACICEPT | PHASE3 | ClinicalTrials.gov | |
| NCT05248659 | SIBEPRENLIMAB | PHASE2/PHASE3 | ClinicalTrials.gov | |
| NCT05248646 | SIBEPRENLIMAB | PHASE3 | ClinicalTrials.gov | |
| NCT04716231 | ATACICEPT | PHASE3 | ClinicalTrials.gov | |
| NCT04287985 | SIBEPRENLIMAB | PHASE2 | 2024-11-21 | ClinicalTrials.gov |
1 to 10 of 23
See all 23 trialsNIH grants753
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TNFSF13 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| R01DK078244 | Molecular Basis of Pathogenicity of IgA1-containing Immune Complexes | 4 | 2025 |
| P01CA155258 | Integrative Oncogenomics of Multiple Myeloma | 3 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 3 | 2025 |
| U19AI057266 | Vaccine and Infection Induced Immunity in the Young and Aged | 3 | 2025 |
| U19AI070535 | Airway Inflammation and Airway Remodeling in Severe Asthma | 3 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 3 | 2025 |
| P30AI050410 | The University of North Carolina Center for AIDS Research | 2 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 753Source NIH's project files
See all 753 nih grantsPapers1,439
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Atacicept: First Approval. | Drugs | 2026 | 42714746 | PubTator, text mining | PubMed |
| Atacicept in IgA nephropathy. | Expert Rev Clin Immunol | 2026 | 42710874 | PubTator, text mining | PubMed |
| TNFSF13 Drives Atherosclerosis Progression by Targeting Macrophage Senescence. | Int J Med Sci | 2026 | 42694578 | PubTator, text mining | PubMed |
| Humoral Response to COVID-19 Vaccines and Infection during Sibeprenlimab Treatment of IgA Nephropathy: Data from the ENVISION Trial. | Clin J Am Soc Nephrol | 2026 | 42275148 | PubTator, text mining | PubMed |
| Association between TNFSF13 SNPs and progression to end-stage renal disease in IgA nephropathy patients. | Int Urol Nephrol | 2026 | 42262683 | PubTator, text mining | PubMed |
| Zigakibart Potently Inhibits A Proliferation-Inducing Ligand-Mediated IgA Production, Addressing IgAN Pathogenesis Root Causes. | Kidney Int Rep | 2026 | 42205925 | PubTator, text mining | PubMed |
| Inflammatory Biomarkers Are Associated with Pain and Functional Impairment in Knee Osteoarthritis Patients: A Cross-Sectional Pilot Study. | J Clin Med | 2026 | 42123198 | PubTator, text mining | PubMed |
Efficacy, safety, and biomarker changes of B-cell activating factor and A proliferation-inducing ligand-targeted therapies in IgA nephropathy: a systematic review and meta-analysis of randomized controlled trials. | J Nephrol | 2026 | 42014363 | PubTator, text mining | PubMed |
| TNFSF13 insufficiency disrupts human colonic epithelial cell growth and associated B cell dynamics. | J Clin Invest | 2026 | 41919502 | PubTator, text mining | PubMed |
| Prediction of depressive episodes based on clinical features, cognitive characteristics, inflammation-related proteins, and EEG data. | Transl Psychiatry | 2026 | 41876463 | PubTator, text mining | PubMed |
1 to 10 of 1,439
See all 1,439 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8741
GET https://conductscience.org/api/genes/v1/8741/patents?page=2