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Gene · 8764

TNFRSF14: TNF receptor superfamily member 14

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TNFRSF14: TNF receptor superfamily member 14. Genes, record 8764. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8764

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Gene

Symbol
TNFRSF14
HGNC
Name
TNF receptor superfamily member 14
HGNC
NCBI Gene ID
8764
NCBI Gene
HGNC ID
HGNC:11912
HGNC
Ensembl
ENSG00000157873
NCBI Gene
Aliases
ATAR, CD270, HVEA, HVEM, LIGHTR, TR2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q92956Tumor necrosis factor receptor superfamily member 142838Ensembl, GeneID, HGNC

Source UniProt

Patents221

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026019692 A22026-01-2221Q92956Espacenet
JP 2026004568 A2026-01-1468659Q92956Espacenet
EP 4650780 A22025-11-197204Q92956Espacenet
EP 4640849 A22025-10-291062Q92956Espacenet
EP 4641201 A22025-10-297134Q92956Espacenet
EP 4628503 A22025-10-0828Q92956Espacenet
JP 2025147176 A2025-10-0613574Q92956Espacenet
JP 2025147176 A2025-10-0616610Q92956Espacenet
JP 2025147176 A2025-10-0616726Q92956Espacenet
EP 4619424 A22025-09-2430Q92956Espacenet

1 to 10 of 221

See all 221 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,851

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTNFRSF14 papersNewest fiscal year
P30CA008748Cancer Center Support Grant312025
P30EY001792P30 Core Grant for Vision Research272025
ZIASC000550Lymphoma Disease Discovery and Definition152025
U19AI070535Airway Inflammation and Airway Remodeling in Severe Asthma132025
P30CA016672Cancer Center Support Grant122025
R01EY024710A new molecular therapy against ocular herpes122025
ZIABC011070Hematopathology Diagnosis92025
P01CA163205Circumventing Barriers to Effective Oncolytic Virotherapy of Malignant Gliomas72025
P30CA010815Consolidated Basic Cancer Research Program72025
P30CA016058Cancer Center Support Grant72025

1 to 10 of 1,851Source NIH's project files

See all 1,851 nih grants

Papers3,537

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
[Diagnosis/Treatment Status and Research Progress of Primary Thyroid Lymphoma--Review].Zhongguo Shi Yan Xue Ye Xue Za Zhi202642802467PubTator, text miningPubMed
Mutant HVEM in lymphoma disrupts BTLA and CD160 regulation of anti-tumor signaling.Front Immunol202642798506PubTator, text miningPubMed
Shared Genetic Basis of Autoimmune Diseases and Follicular Lymphoma by Mendelian Randomization and Multi-Omics.Genes (Basel)202642792925PubTator, text miningPubMed
Beyond PD-L1/PD-1: expression of PVR/TIGIT and TNFRSF14/BTLA axes in response to Helicobacter pylori and in gastric cancer lesions.Immunohorizons202642772936PubTator, text miningPubMed
A multi-omics integrative analyses reveals CYBB-mediated apoptotic and immune dysregulation as a key target of berberine in diffuse large B-cell lymphoma.Front Pharmacol202642730162PubTator, text miningPubMed
Single cell mapping of B and T cell dynamics in breast cancer lymph node metastasis.Front Bioinform202642656703PubTator, text miningPubMed
The BTLA/HVEM axis as a key regulator for stratified functional cure in chronic hepatitis B.Front Immunol202642638743PubTator, text miningPubMed
Investigating the role of costimulatory domains in enhancing CAR-T cell persistence in TNBC.Cancer Gene Ther202642629367PubTator, text miningPubMed
Anti-4CB1: A Novel Selective HVEM-Blocking Antibody Enhancing T-Cell and Macrophage Immunity Against Solid Tumors.Mol Cancer Ther202642617197PubTator, text miningPubMed
Plasma Metabolomic and Proteomic Profiling of the Mechanisms Underlying the Cumulative Impact of Co-occurring Psychiatric Disorders on Atopic Dermatitis.Acta Derm Venereol202642549601PubTator, text miningPubMed

1 to 10 of 3,537

See all 3,537 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8764

GET https://conductscience.org/api/genes/v1/8764/patents?page=2