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FADD: Fas associated via death domain

1 protein, 81 patents, 0 drugs, 0 trials, 3,976 NIH grants and 8,672 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolFADDHGNC
NameFas associated via death domainHGNC
NCBI Gene ID8772NCBI Gene
HGNC IDHGNC:3573HGNC
EnsemblENSG00000168040NCBI Gene
AliasesGIG3, IMD90, MORT1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q13158FAS-associated death domain protein20818Ensembl, GeneID, HGNCUniProt

Patents 81

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026219974 A12026-10-224Q13158Espacenet
EP 4691494 A12026-02-117Q13158Espacenet
EP 4650780 A22025-11-194105Q13158Espacenet
JP 2025147176 A2025-10-0616516Q13158Espacenet
JP 2025517970 A2025-06-124105Q13158Espacenet
KR 1020250036258 A2025-03-1335Q13158Espacenet
JP 2025028160 A2025-02-2816516Q13158Espacenet
KR 1020250010750 A2025-01-2116516Q13158Espacenet
EP 4484957 A12025-01-01105Q13158Espacenet
JP 2024123008 A2024-09-106182Q13158Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3976

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant412,025NIH's project files
P30CA047904Cancer Center Support Grant222,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)202,025NIH's project files
P30CA008748Cancer Center Support Grant182,025NIH's project files
R37AI044828Survival Function of the Fadd-Caspase-8-Flip Complex - MERIT Extension172,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase152,025NIH's project files
R01AI124346Innate immune signaling and stress response152,025NIH's project files
R37AI101935Inflammatory Caspases in Innate Immunity and Inflammation152,025NIH's project files
P20GM103434West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE)122,025NIH's project files
P30CA016059Massey Cancer Center - Cancer Center Support Grant102,025NIH's project files

Papers 8672

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42791244PubTator, text miningPubMed
42760759PubTator, text miningPubMed
42722396PubTator, text miningPubMed
42702898PubTator, text miningPubMed
42694396PubTator, text miningPubMed
42677111PubTator, text miningPubMed
42673753PubTator, text miningPubMed
42556471PubTator, text miningPubMed
42518285PubTator, text miningPubMed
42518252PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license