Gene · 8788
DLK1: delta like non-canonical Notch ligand 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DLK1: delta like non-canonical Notch ligand 1. Genes, record 8788. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8788
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P80370 | Protein delta homolog 1 | 383 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents52
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 43561 | P80370 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6523 | P80370 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 935 | P80370 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 6269 | P80370 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 4276 | P80370 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1271 | P80370 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6187 | P80370 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1271 | P80370 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6187 | P80370 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 935 | P80370 | Espacenet |
1 to 10 of 52
See all 52 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,540
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DLK1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 15 | 2025 |
| P30DK040561 | Boston Area Nutrition Obesity Research Center (NORC) | 14 | 2025 |
| R01HD082314 | Deciphering the functional role of MKRN3 in puberty and reproduction | 12 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 11 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 10 | 2025 |
| P30ES025128 | Center for Human Health and the Environment (CHHE) | 9 | 2025 |
| P30DK036836 | Diabetes Research Center | 7 | 2025 |
| P30DK026743 | UCSF Liver Center | 6 | 2025 |
| P20GM121301 | Phase II COBRE in Mesenchymal and Neural Regulation of Metabolic Networks | 5 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 2,540Source NIH's project files
See all 2,540 nih grantsPapers3,998
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Obesity, Oxidative Stress, and Inflammation in Precocious Puberty: Do All Roads Lead to the Hypothalamus? | Int J Mol Sci | 2026 | 42794587 | PubTator, text mining | PubMed |
| Interindividual variability of sperm DNA methylation is associated with reduced fecundability in couples attempting natural conception. | Hum Reprod | 2026 | 42786259 | PubTator, text mining | PubMed |
| Transcriptomic and miRNA-Target Pathway Analysis of the DLK1-DIO3 Imprinted microRNA Cluster in Chronic Lymphocytic Leukemia. | Diseases | 2026 | 42783213 | PubTator, text mining | PubMed |
| A methanogen hydrolase reveals the structure of archaeal peptidoglycan. | Nature | 2026 | 42778595 | PubTator, text mining | PubMed |
| Delayed late ventricular depolarization is associated with inflammation in epicardial Fat Among females: a New avenue in cardiac electrophysiology. | Front Cardiovasc Med | 2026 | 42769221 | PubTator, text mining | PubMed |
| High-Throughput Characterization of Human Fibroblast Responses to a Panel of Staphylococcus aureus Antigen Proteins Using Olink Proteomics. | Open Forum Infect Dis | 2026 | 42751267 | PubTator, text mining | PubMed |
| Syndrome differentiation and treatment of pediatric central precocious puberty: role of the spleen-kidney axis. | Front Immunol | 2026 | 42713456 | PubTator, text mining | PubMed |
| Reciprocal, methylation-dependent binding of Zfp57 and Gzf1 safeguards Dlk1-Dio3 imprinting during developmental reprogramming. | Nat Commun | 2026 | 42686776 | PubTator, text mining | PubMed |
| Establishment of a ZFP64::NCOA3 fusion-positive spindle cell/sclerosing rhabdomyosarcoma organoid model and evaluation of fusion-gene dependency. | Hum Cell | 2026 | 42622717 | PubTator, text mining | PubMed |
| Senescent microglia with shortened telomeres secrete soluble DLK1 to induce aging-associated hypomyelination and neuronal dysfunction. | Neuron | 2026 | 42580340 | PubTator, text mining | PubMed |
1 to 10 of 3,998
See all 3,998 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8788
GET https://conductscience.org/api/genes/v1/8788/patents?page=2