ConductScience.org, home

Gene · 8794

TNFRSF10C: TNF receptor superfamily member 10c

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. TNFRSF10C: TNF receptor superfamily member 10c. Genes, record 8794. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8794

On this page

Gene

Symbol
TNFRSF10C
HGNC
Name
TNF receptor superfamily member 10c
HGNC
NCBI Gene ID
8794
NCBI Gene
HGNC ID
HGNC:11906
HGNC
Ensembl
ENSG00000173535
NCBI Gene
Aliases
CD263, DCR1, DCR1-TNFR, DcR1, LIT, TRAIL-R3, TRAILR3, TRID
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O14798Tumor necrosis factor receptor superfamily member 10C2590Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1468648O14798Espacenet
EP 4650780 A22025-11-197360O14798Espacenet
JP 2025529142 A2025-09-044997O14798Espacenet
EP 4606428 A22025-08-2730O14798Espacenet
US 12392775 B22025-08-196O14798Espacenet
US 12371689 B22025-07-294997O14798Espacenet
JP 2025517970 A2025-06-127360O14798Espacenet
EP 4549941 A12025-05-078O14798Espacenet
EP 4491229 A22025-01-15302O14798Espacenet
EP 4484956 A22025-01-016O14798Espacenet

1 to 10 of 35

See all 35 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants943

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTNFRSF10C papersNewest fiscal year
P30CA016672Cancer Center Support Grant132025
P30CA008748Cancer Center Support Grant92025
P30CA047904Cancer Center Support Grant52025
ZIASC007263Activating Cell Death Pathways in Breast Cancer Cells52025
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)42025
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study32025
P20GM103434West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE)32025
P30CA014051Cancer Center Support (Core) Grant32025
P30CA016056Roswell Park Cancer Center Support Grant32025
P30CA021765Cancer Center Support Grant (CCSG)32025

1 to 10 of 943Source NIH's project files

See all 943 nih grants

Papers1,743

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Distinct responses of COL17A1 nonsense variants to readthrough drugs and NOG as a novel enhancer in junctional epidermolysis bullosa.Mol Ther Nucleic Acids202642824587PubTator, text miningPubMed
Cardiovascular peptide markers are associated with age-related macular degeneration in the Bialystok PLUS general population cohort.Sci Rep202642310032PubTator, text miningPubMed
Identification and validation of programmed cell death-related genes in osteosarcoma: inhibiting CIB1 as a promising therapeutic strategy.BMC Cancer202642298489PubTator, text miningPubMed
Epigenetic Regulation and Immune Associations of TRAIL Decoy Receptors TNFRSF10C and TNFRSF10D in Glioblastoma: A Multi-omic Analysis.Cureus202642037836PubTator, text miningPubMed
Foundation and Multimodal Models for Drug Discovery in Molecular Informatics: Principles, Evaluation, and Practical Guidance.Mol Inform202641877557PubTator, text miningPubMed
Heterogeneity in inflammatory responses to endotoxin at the fetomaternal interface.J Immunol202641847862PubTator, text miningPubMed
Low thermal inertia of carbonaceous asteroid Bennu driven by cracks observed in returned samples.Nat Commun202641844589PubTator, text miningPubMed
New Insights into the Role of NF-κB in Hepatitis B Virus Infection.Int J Biol Sci202641800244PubTator, text miningPubMed
Advances in Targeted and Immunotherapy for High-Risk Cutaneous Malignancies.Oncol Res202641799519PubTator, text miningPubMed
Jurkat T-Cell Antigen-Independent Elimination of PMA-Activated Neuroblastoma Cells Is Triggered by CCL2/CCR2, Depends Upon Lipid Raft LFA1/ICAM1 Immune Synapses, Is Mediated by m-TRAIL and Is Augmented by the TrkAIII Oncoprotein.
Int J Mol Sci202641752106PubTator, text miningPubMed

1 to 10 of 1,743

See all 1,743 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8794

GET https://conductscience.org/api/genes/v1/8794/patents?page=2