Gene · 8801
SUCLG2: succinate-CoA ligase GDP-forming subunit beta
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SUCLG2: succinate-CoA ligase GDP-forming subunit beta. Genes, record 8801. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8801
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q96I99 | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial | 432 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents19
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4752548 A1 | 2026-06-03 | 12 | Q96I99 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 4500 | Q96I99 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 4047 | Q96I99 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 4047 | Q96I99 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 4500 | Q96I99 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 84794 | Q96I99 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 187765 | Q96I99 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 2512 | Q96I99 | Espacenet |
| EP 3504344 A1 | 2019-07-03 | 1245 | Q96I99 | Espacenet |
| JP 2017121240 A | 2017-07-13 | 54694 | Q96I99 | Espacenet |
1 to 10 of 19
See all 19 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,762
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SUCLG2 papers | Newest fiscal year |
|---|---|---|---|
| R35GM128641 | Structure, pharmacology and signaling of G protein-coupled receptors (GPCRs) in inflammation | 12 | 2025 |
| R01MH112205 | Molecular Details of Psychoactive Drug Actions | 10 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 9 | 2025 |
| R01DA036596 | Regulation of Neuronal GPCR Signaling | 8 | 2025 |
| R01HL016037 | Molecular Regulation of Cardiovascular 7 TM Receptors | 6 | 2025 |
| R35GM118105 | Negative and positive feedback in cell signaling | 6 | 2025 |
| R35GM122481 | Development and Testing of New Computational Methods for Ligand Discovery and Mechanism | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| R01HL117913 | The NOTCH Signaling Pathway in Large Vessel Vasculitis | 5 | 2025 |
| R01HL142068 | T Cell Immunity in Giant Cell Arteritis | 5 | 2025 |
1 to 10 of 1,762Source NIH's project files
See all 1,762 nih grantsPapers2,055
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Multi-omic profiling and pathways related to changes in liver histology after Roux-en-Y gastric bypass: a longitudinal study. | EBioMedicine | 2026 | 42810054 | PubTator, text mining | PubMed |
| Functional diversity in G-protein signalling: In-silico study of G-protein γ subunit induced behavioural alteration in G-protein β subunit hotspot. | Int J Biol Macromol | 2026 | 42790561 | PubTator, text mining | PubMed |
| SUCLG2 contributes to platinum resistance in lung adenocarcinoma through enhancing succinylation of GAC and glutamine metabolism. | Apoptosis | 2026 | 42776318 | PubTator, text mining | PubMed |
| NSUN2 Promotes Cancer Immune Evasion via Its Moonlighting Function Acting on Metabolic Reprogramming. | Cancer Commun (Lond) | 2026 | 42620795 | PubTator, text mining | PubMed |
| The SIRT5-SUCLG2 desuccinylation axis delays ovarian aging via a mitochondrial-epigenetic regulatory mechanism. | Nat Commun | 2026 | 42457680 | PubTator, text mining | PubMed |
| A telomerase-SUCLG2 signaling axis drives drug resistance by protecting persister cells. | Cell Rep | 2026 | 42418322 | PubTator, text mining | PubMed |
| Lactate as a Chemical Modification on Proteins and Metabolites. | Annu Rev Biochem | 2026 | 42331744 | PubTator, text mining | PubMed |
| Structural composition and functional diversities of G proteins in fungi. | Mycology | 2026 | 42305152 | PubTator, text mining | PubMed |
| Co-targeting EGFR and SUCLG2 disrupts a nuclear transcriptional program driving neuroendocrine differentiation and TKI resistance in castration-resistant prostate cancer. | Cell Commun Signal | 2026 | 42252434 | PubTator, text mining | PubMed |
| Extra-large G proteins and their roles in plant development and responses to environmental stresses. | Front Plant Sci | 2026 | 42164782 | PubTator, text mining | PubMed |
1 to 10 of 2,055
See all 2,055 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8801
GET https://conductscience.org/api/genes/v1/8801/patents