ConductScience.org, home

Gene · 8817

FGF18: fibroblast growth factor 18

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. FGF18: fibroblast growth factor 18. Genes, record 8817. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8817

On this page

Gene

Symbol
FGF18
HGNC
Name
fibroblast growth factor 18
HGNC
NCBI Gene ID
8817
NCBI Gene
HGNC ID
HGNC:3674
HGNC
Ensembl
ENSG00000156427
NCBI Gene
Aliases
FGF-18, ZFGF5
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O76093Fibroblast growth factor 182071Ensembl, GeneID, HGNC

Source UniProt

Patents209

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4791763 A12026-08-191O76093Espacenet
EP 4774397 A12026-07-15111O76093Espacenet
EP 4705273 A22026-03-11220O76093Espacenet
EP 4650780 A22025-11-192921O76093Espacenet
JP 2025147176 A2025-10-065275O76093Espacenet
JP 2025529142 A2025-09-046370O76093Espacenet
US 12371689 B22025-07-296370O76093Espacenet
JP 2025105692 A2025-07-101O76093Espacenet
US 12332250 B22025-06-171O76093Espacenet
US 12332251 B22025-06-171O76093Espacenet

1 to 10 of 209

See all 209 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants882

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFGF18 papersNewest fiscal year
P30CA016672Cancer Center Support Grant62025
R01AR031737Regulation of Epidermal Development and Differentiation-Renewal62025
R01AR050452Skin Stem Cells and Their Niche Interactions62025
P30AR069619Overall: Resource-based Center for Musculoskeletal Disorders Research (Overall Application)42025
ZIAES100485Mechanism Of Action And Functions Of The Gli-related Proteins Glis 1-342025
P30AR073752Washington University Rheumatic Diseases Research Resource-based Center32025
P30CA008748Cancer Center Support Grant32025
P30CA047904Cancer Center Support Grant32025
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)32025
P42ES010356Duke University Superfund Research Center - Developmental Co-Exposures: Mechanisms, Outcomes, and Remediation32025

1 to 10 of 882Source NIH's project files

See all 882 nih grants

Papers1,397

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
FGF18 aggravates angiotensin II-induced vascular smooth muscle cell dysfunction via the FGFR-ERK/AKT-GSK3β/β-catenin pathway.J Thorac Dis202642724301PubTator, text miningPubMed
Growth Plate Morphogens as Potential Modulators of Cellular Tissue Remodeling by Annulus Fibrosus Cells.JOR Spine202642633138PubTator, text miningPubMed
microRNA-145-3p/CTNND1/FGF18 Signaling Pathway Regulates Apoptosis and Extracellular Matrix Degradation in the Vaginal Wall Fibroblasts of Patients with Pelvic Organ Prolapse.Gynecol Obstet Invest202642607023PubTator, text miningPubMed
A Mechanistic Review of Environmental Stressor to Decode Their Effect on Congenital Malformations: A Developmental Toxicity.J Biochem Mol Toxicol202642573050PubTator, text miningPubMed
Linking environmental cadmium to pterygium pathogenesis: Mechanistic insights from fibroblast proliferation and calcium antagonism.Ecotoxicol Environ Saf202642480141PubTator, text miningPubMed
Immunoinflammatory Profile of FGF-18, IL-35 and Glutamic Acid Decarboxylase in Patients With Diabetic Foot Ulcers.Int Wound J202642397137PubTator, text miningPubMed
FGF18 mediates fibroblast-leukemia cross talk to promote acute myeloid leukemia progression.Blood202642360909PubTator, text miningPubMed
Fgf18 marks reserve skeletal progenitors in the fibrous periosteum contributing to bone fracture repair.Cell Rep202642284141PubTator, text miningPubMed
Fibroblast Growth Factor-18 (FGF-18) Attenuates ox-LDL-Induced Endothelial Inflammation and Monocyte Adhesion by Inhibiting TRIM28.J Interferon Cytokine Res202642212430PubTator, text miningPubMed
Modulation of WNT and FGF18 enhances yield and subtype identity of hPSC-derived midbrain dopamine neurons.J Clin Invest202642138078PubTator, text miningPubMed

1 to 10 of 1,397

See all 1,397 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8817

GET https://conductscience.org/api/genes/v1/8817/patents?page=2