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Gene · 8824

CES2: carboxylesterase 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CES2: carboxylesterase 2. Genes, record 8824. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8824

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Gene

Symbol
CES2
HGNC
Name
carboxylesterase 2
HGNC
NCBI Gene ID
8824
NCBI Gene
HGNC ID
HGNC:1864
HGNC
Ensembl
ENSG00000172831
NCBI Gene
Aliases
CE-2, CES2A1, PCE-2, iCE
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O00748Cocaine esterase5590Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-195139O00748Espacenet
JP 2025529142 A2025-09-04910O00748Espacenet
US 12371689 B22025-07-29910O00748Espacenet
JP 2025517970 A2025-06-125139O00748Espacenet
EP 4487869 A22025-01-08230O00748Espacenet
KR 1020240027895 A2024-03-04422O00748Espacenet
JP 2023036863 A2023-03-14422O00748Espacenet
US 10918740 B22021-02-161966O00748Espacenet
US 10869935 B22020-12-221966O00748Espacenet
JP 2020518613 A2020-06-25422O00748Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants886

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCES2 papersNewest fiscal year
P30CA021765Cancer Center Support Grant (CCSG)212025
P30CA091842Cancer Center Support Grant62025
P30CA016672Cancer Center Support Grant52025
R01DK102619Mechanisms Underlying the Pathogenesis of Non-alcoholic Fatty Liver Disease52025
R01HD081299Ontogeny of drug transport52025
P30CA008748Cancer Center Support Grant42025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)32025
R01CA142746Subcellular enzyme-instructed self-assembly for molecular anticancer nanomedicines32025
R25CA023944PEDIATRIC ONCOLOGY EDUCATION (YEARS 38 - 42)32025
T32AA007462Training Grant on Genetic Aspects of Alcoholism32025

1 to 10 of 886Source NIH's project files

See all 886 nih grants

Papers2,091

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Personalizing mycophenolate therapy: genetic determinants and practical limited sampling strategy for pediatric lupus nephritis.Eur J Clin Pharmacol202642823492PubTator, text miningPubMed
Liquid-free ion-conductive elastomers with bioinspired oriented structures based on bacterial cellulose for dual-mode humidity sensing and energy harvesting.Carbohydr Polym202642785866PubTator, text miningPubMed
Correction to "Pacing the Impossible: ICE- and Voltage-Guided Atrial Leadless Pacemaker Implantation in Double Mechanical Valve Disease".J Arrhythm202642746164PubTator, text miningPubMed
Engineered human adipose-derived stem cells delivering carboxylesterase and TRAIL for castration-resistant prostate cancer: Translational synthesis.Investig Clin Urol202642683853PubTator, text miningPubMed
Comparison of the Ice-Regulating Properties of Side-Zwitterionic Poly(vinyl alcohol)-Poly(l-methionine) and Poly(ethylene glycol)-Poly(l-methionine).Langmuir202642674536PubTator, text miningPubMed
Structure-based optimization, in vitro profiling, and ADMET prediction of Celastrol derivatives as potent prolyl endopeptidase inhibitors.Bioorg Chem202642673716PubTator, text miningPubMed
ICE Activity Tied to Disruptions in Pediatric Care.JAMA202642664017PubTator, text miningPubMed
The brassinosteroid-responsive transcription factor CmBEEL1 through integrating ICE1 cascade and ROS homeostasis enhances cold tolerance in Chrysanthemum.Plant Physiol Biochem202642607376PubTator, text miningPubMed
In Silico Methodology for Human Carboxylesterases 1 and 2 Isoforms Substrate Selectivity Study.Methods Mol Biol202642562991PubTator, text miningPubMed
ICE-guided left atrial appendage closure: Reassuring real-world outcomes in an era of conflicting randomized evidence.Int J Cardiol202642503336PubTator, text miningPubMed

1 to 10 of 2,091

See all 2,091 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8824

GET https://conductscience.org/api/genes/v1/8824/patents?page=2