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SOCS2: suppressor of cytokine signaling 2
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Gene · 8835

Papers2,451

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,451

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TitleJournalYearPMIDFound bySource
SOCS2 Downregulation Is Associated with a Ferro-Aging-Related Transcriptomic Signature in Proximal Tubular Cells in Chronic Kidney Disease.Biomedicines202642792788PubTator, text miningPubMed
Differential regulation of SOCS signalling and immunoproteasome pathways by JAK inhibitors and TNF inhibitors in rheumatoid arthritis.Arthritis Res Ther202642745343PubTator, text miningPubMed
Integrated Transcriptomic Analyses Identify Four Prognosis-Associated Genes in Hepatocellular Carcinoma.Int J Mol Sci202642737438PubTator, text miningPubMed
Extracellular Vesicles in Cardiovascular Disease: Intercellular Signaling, Liquid Biopsy Biomarkers, and Therapeutic Translation.Circ Res202642594169PubTator, text miningPubMed
Decoding the Complexity of Hepatocellular Carcinoma: Clinical Challenges and Targeting HuR as a Novel Therapeutic Strategy.Livers202642583674PubTator, text miningPubMed
SIRT6 Aggravates Psoriasiform Skin Inflammation Through Modulation of the SOCS2-STAT1/3 Pathway.J Inflamm Res202642577923PubTator, text miningPubMed
Single cell multi-omics enables high-resolution identification and functional purification of human acute myeloid leukemia stem cells.bioRxiv202642523402PubTator, text miningPubMed
Prognostic Relevance of Neddylation-Related Genes in Hepatocellular Carcinoma.J Hepatocell Carcinoma202642460258PubTator, text miningPubMed
Identification of circadian rhythm-associated key genes in metabolic dysfunction-associated fatty liver disease.Clin Exp Med202642329455PubTator, text miningPubMed
SOCS2 inhibits neutrophil N1 polarization to attenuate cardiomyocyte PANoptosis through HSPA8 ubiquitination in atrial fibrillation.Biochem Biophys Res Commun202642251819PubTator, text miningPubMed
The Janus-faced suppressor of cytokine signaling 2-antisense transcript 1 in human cancers: from molecular mechanisms to clinical translation.Drug Discov Today202642229630PubTator, text miningPubMed
Reduced socs2 expression and elevated IL-4/IL-23 levels in multiple sclerosis patients: Implications for immune dysregulation.Hum Immunol202642202484PubTator, text miningPubMed
Silkworm SOCS2 Differentially Promotes Multiple Steps of BmNPV Proliferation and Modulates the mRNA Expression of SOCS-STAT Network Components.Insects202642188169PubTator, text miningPubMed
Abnormal Expression of Suppressor of Cytokine Signalling (SOCS) Molecules Contributes to the Development of Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis.Scand J Immunol202642067992PubTator, text miningPubMed
Investigating the molecular mechanism of selective inhibition of JAK1/TYK2 by SOCS1/SOCS3 using molecular dynamics simulations.Phys Chem Chem Phys202642046978PubTator, text miningPubMed
Ordinal GWAS analysis of the frailty phenotype identified a novel locus at 12q22 that underscores the role of the neurological and immune systems.NPJ Aging202642020437PubTator, text miningPubMed
Ailanthone targets the EGR3-SOCS2 regulatory pathway to suppress vasculogenic mimicry in prostate cancer.Biochem Pharmacol202641997257PubTator, text miningPubMed
Transcriptomic Determinants of Circulating Immunity Predict Immune-Related Adverse Events (irAEs) in Cancer Patients Receiving PD-1/PD-L1 Blockade.Thorac Cancer202641920053PubTator, text miningPubMed
The JMJD family histone demethylases: structure, mechanism of action, diseases and therapeutic targets.Mol Biomed202641857315PubTator, text miningPubMed
IL-7/IL-15/IL-21 cytokine-fusion scaffold generates highly functional CAR T cells enriched in long-lived T memory stem cells.Sci Adv202641824575PubTator, text miningPubMed

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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