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GGH: gamma-glutamyl hydrolase

1 protein, 56 patents, 0 drugs, 0 trials, 7,021 NIH grants and 31,309 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolGGHHGNC
Namegamma-glutamyl hydrolaseHGNC
NCBI Gene ID8836NCBI Gene
HGNC IDHGNC:4248HGNC
EnsemblENSG00000137563NCBI Gene
AliasesGATD10, GHNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q92820Gamma-glutamyl hydrolase3181Ensembl, GeneID, HGNCUniProt

Patents 56

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1447289Q92820Espacenet
EP 4650780 A22025-11-191782Q92820Espacenet
EP 4641203 A22025-10-2956Q92820Espacenet
JP 2025147176 A2025-10-065901Q92820Espacenet
JP 2025529142 A2025-09-046486Q92820Espacenet
US 12371689 B22025-07-296486Q92820Espacenet
JP 2025517967 A2025-06-1256Q92820Espacenet
JP 2025517970 A2025-06-121782Q92820Espacenet
JP 2025028160 A2025-02-285901Q92820Espacenet
KR 1020250017230 A2025-02-0456Q92820Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 7021

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant382,025NIH's project files
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)322,025NIH's project files
P30EY001792P30 Core Grant for Vision Research282,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)242,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award242,025NIH's project files
R01AG059779Combining GHR antagonism with life extending compounds: a search for synergies212,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)192,025NIH's project files
P30CA016672Cancer Center Support Grant152,025NIH's project files
P30DK020541NYR-Diabetes Research Center (NYR-DRC)142,025NIH's project files
P51OD011107California National Primate Research Center142,025NIH's project files

Papers 31309

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824949PubTator, text miningPubMed
42812268PubTator, text miningPubMed
42801556PubTator, text miningPubMed
42793016PubTator, text miningPubMed
42789669PubTator, text miningPubMed
42788125PubTator, text miningPubMed
42784308PubTator, text miningPubMed
42780278PubTator, text miningPubMed
42772013PubTator, text miningPubMed
42759849PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license