Gene · 8840
CCN4: cellular communication network factor 4
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CCN4: cellular communication network factor 4. Genes, record 8840. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8840
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O95388 | CCN family member 4 | 367 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents92
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 69925 | O95388 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1298 | O95388 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 14260 | O95388 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 8075 | O95388 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 8075 | O95388 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1298 | O95388 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 14260 | O95388 | Espacenet |
| JP 2025011102 A | 2025-01-23 | 1 | O95388 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 14260 | O95388 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 14267 | O95388 | Espacenet |
1 to 10 of 92
See all 92 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants732
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CCN4 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| U54GM104942 | West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve Health | 5 | 2025 |
| P20GM103434 | West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE) | 4 | 2025 |
| ZIADE000380 | The role of stem cells in skeletal health and disease | 4 | 2025 |
| P20GM121322 | Tumor Microenvironment-TME CoBRE | 3 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 3 | 2025 |
| P30CA077598 | Cancer Center Support Grant | 3 | 2025 |
| P30AG028716 | Duke Claude D. Pepper Older Americans Independence Center | 2 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 2 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 2 | 2025 |
1 to 10 of 732Source NIH's project files
See all 732 nih grantsPapers1,415
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| E3 ubiquitin ligase MAGI3‑mediated TAZ ubiquitination suppresses the non‑small cell lung cancer occurrence and development by targeting the Wnt pathway. | Int J Oncol | 2026 | 42757476 | PubTator, text mining | PubMed |
| WISP1 Drives Intestinal Fibrosis in Crohn's Disease via Metabolic and Rho/ROCK/MRTF-Mediated Cytoskeletal Remodeling. | Gastroenterology | 2026 | 42612881 | PubTator, text mining | PubMed |
| Chasing the FoxO in Metabolic Disorders: Novel Considerations for Oxidative Stress, Programmed Cell Death, Wnt, and the Gut Microbiome. | Antioxidants (Basel) | 2026 | 42510625 | PubTator, text mining | PubMed |
| Cardiorespiratory fitness, adiposity, and metabolic risk in breast cancer survivors: links with circulating WISP-1 and WISP-3. | Korean J Physiol Pharmacol | 2026 | 42481430 | PubTator, text mining | PubMed |
| Genomic Evidence Links Inflammation to Residual Pulmonary Vascular Obstruction and Risk of Pulmonary Embolism Recurrence. | medRxiv | 2026 | 42465927 | PubTator, text mining | PubMed |
| Transcriptomic remodeling of bone marrow mesenchymal stromal cells in pediatric B-cell acute lymphoblastic leukemia: a four-gene signature. | Transl Pediatr | 2026 | 42433948 | PubTator, text mining | PubMed |
| In Vivo ORF Overexpression Screening Identifies CCN4 as a Regulator of Glioblastoma Growth Validated Across Multiple Models. | Int J Mol Sci | 2026 | 42352948 | PubTator, text mining | PubMed |
| A Scoping Review of Emerging Treatments in the Pipeline for Idiopathic Pulmonary Fibrosis: Future Perspectives. | Biomedicines | 2026 | 42351721 | PubTator, text mining | PubMed |
| High-Throughput Olink Proteomics Elucidates the Immuno-Neurological Landscape of Gastric Cancer. | J Proteome Res | 2026 | 42329880 | PubTator, text mining | PubMed |
| Immunoinformatics-guided design of a multi-epitope vaccine targeting WISP1 for gastric cancer. | BMC Biotechnol | 2026 | 42237149 | PubTator, text mining | PubMed |
1 to 10 of 1,415
See all 1,415 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8840
GET https://conductscience.org/api/genes/v1/8840/patents?page=2