Gene · 8846
ALKBH1: alkB homolog 1, histone H2A dioxygenase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ALKBH1: alkB homolog 1, histone H2A dioxygenase. Genes, record 8846. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8846
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13686 | Nucleic acid dioxygenase ALKBH1 | 389 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents20
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 37096 | Q13686 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 354 | Q13686 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 747 | Q13686 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5454 | Q13686 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5454 | Q13686 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 354 | Q13686 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 4144 | Q13686 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 747 | Q13686 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 747 | Q13686 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 754 | Q13686 | Espacenet |
1 to 10 of 20
See all 20 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,054
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ALKBH1 papers | Newest fiscal year |
|---|---|---|---|
| RM1HG008935 | Center for dynamic RNA epitranscriptomes - Renewal | 15 | 2025 |
| R01GM049758 | Structure and Function of Metalloenzymes | 12 | 2025 |
| R01CA080024 | Intra and Extra-Chromosomal Probes for Mutagenesis by Carcinogens | 11 | 2025 |
| P20GM103430 | Rhode Island IDeA Network of Biomedical Research Excellence | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 6 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 6 | 2025 |
| R01HG006827 | Labeling and sequencing of 5hmC and 5mC in DNA-Renewal | 6 | 2025 |
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 1,054Source NIH's project files
See all 1,054 nih grantsPapers2,913
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Integrated Analysis of Paired Crude Oil and Produced Water Reveals Stress-Tolerant Hydrocarbon-Degrading Bacteria with Bioremediation Potential. | Microorganisms | 2026 | 42795562 | PubTator, text mining | PubMed |
| Persistent expression of recipient-type ABH antigen following ABO-incompatible stem cell transplantation despite complete donor-type chimerism. | Blood Cell Ther | 2026 | 42707853 | PubTator, text mining | PubMed |
| Bioorthogonal Regulation of Negatively Charged Protein Side Chains in Living Systems. | J Am Chem Soc | 2026 | 42479951 | PubTator, text mining | PubMed |
| Ecosystem-scale genomic and metatranscriptomic evidence for a coupled, active short-term hydrocarbon cycle in the marine photic ocean. | Appl Environ Microbiol | 2026 | 42478814 | PubTator, text mining | PubMed |
| Three catalytic frameworks, one engineering logic: Bottlenecks and design levers in pesticide-degrading hydrolases. | Biotechnol Adv | 2026 | 42456795 | PubTator, text mining | PubMed |
| Salinity-driven microbial adaptation of hydrocarbon-degrading communities in coastal sediments. | mSphere | 2026 | 42390233 | PubTator, text mining | PubMed |
| Niraparib promotes ferroptosis by inhibiting TM4SF1 expression through ALKBH1-mediated 6mA modification in BRCA wild-type ovarian cancer. | Front Pharmacol | 2026 | 42305440 | PubTator, text mining | PubMed |
| pH Tunes the DNA Repair Efficiency and Strand Preference of the AlkB Family Enzymes. | Chem Res Toxicol | 2026 | 42257680 | PubTator, text mining | PubMed |
| ALKBH4 confers ferroptosis resistance and drives tumorigenesis via dysregulation of GPX4 in breast cancer cells. | In Vitro Cell Dev Biol Anim | 2026 | 42207440 | PubTator, text mining | PubMed |
| Substrate selectivity of the human RNA m5C methyltransferase NSUN2. | Nature | 2026 | 42203868 | PubTator, text mining | PubMed |
1 to 10 of 2,913
See all 2,913 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8846
GET https://conductscience.org/api/genes/v1/8846/patents