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Gene · 8846

ALKBH1: alkB homolog 1, histone H2A dioxygenase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ALKBH1: alkB homolog 1, histone H2A dioxygenase. Genes, record 8846. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8846

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Gene

Symbol
ALKBH1
HGNC
Name
alkB homolog 1, histone H2A dioxygenase
HGNC
NCBI Gene ID
8846
NCBI Gene
HGNC ID
HGNC:17911
HGNC
Ensembl
ENSG00000100601
NCBI Gene
Aliases
ABH, ABH1, ALKBH, alkB, hABH
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13686Nucleic acid dioxygenase ALKBH13893Ensembl, GeneID, HGNC

Source UniProt

Patents20

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1437096Q13686Espacenet
EP 4650780 A22025-11-19354Q13686Espacenet
JP 2025147176 A2025-10-06747Q13686Espacenet
JP 2025529142 A2025-09-045454Q13686Espacenet
US 12371689 B22025-07-295454Q13686Espacenet
JP 2025517970 A2025-06-12354Q13686Espacenet
JP 2025062604 A2025-04-144144Q13686Espacenet
JP 2025028160 A2025-02-28747Q13686Espacenet
KR 1020250010750 A2025-01-21747Q13686Espacenet
JP 2024109657 A2024-08-14754Q13686Espacenet

1 to 10 of 20

See all 20 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,054

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleALKBH1 papersNewest fiscal year
RM1HG008935Center for dynamic RNA epitranscriptomes - Renewal152025
R01GM049758Structure and Function of Metalloenzymes122025
R01CA080024Intra and Extra-Chromosomal Probes for Mutagenesis by Carcinogens112025
P20GM103430Rhode Island IDeA Network of Biomedical Research Excellence62025
P30CA016672Cancer Center Support Grant62025
P30CA033572Cancer Center Support Grant62025
P30CA068485Cancer Center Support Grant62025
R01HG006827Labeling and sequencing of 5hmC and 5mC in DNA-Renewal62025
P01CA092584Structural Cell Biology of DNA Repair Machines52025
P30CA008748Cancer Center Support Grant52025

1 to 10 of 1,054Source NIH's project files

See all 1,054 nih grants

Papers2,913

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrated Analysis of Paired Crude Oil and Produced Water Reveals Stress-Tolerant Hydrocarbon-Degrading Bacteria with Bioremediation Potential.Microorganisms202642795562PubTator, text miningPubMed
Persistent expression of recipient-type ABH antigen following ABO-incompatible stem cell transplantation despite complete donor-type chimerism.Blood Cell Ther202642707853PubTator, text miningPubMed
Bioorthogonal Regulation of Negatively Charged Protein Side Chains in Living Systems.J Am Chem Soc202642479951PubTator, text miningPubMed
Ecosystem-scale genomic and metatranscriptomic evidence for a coupled, active short-term hydrocarbon cycle in the marine photic ocean.Appl Environ Microbiol202642478814PubTator, text miningPubMed
Three catalytic frameworks, one engineering logic: Bottlenecks and design levers in pesticide-degrading hydrolases.Biotechnol Adv202642456795PubTator, text miningPubMed
Salinity-driven microbial adaptation of hydrocarbon-degrading communities in coastal sediments.mSphere202642390233PubTator, text miningPubMed
Niraparib promotes ferroptosis by inhibiting TM4SF1 expression through ALKBH1-mediated 6mA modification in BRCA wild-type ovarian cancer.Front Pharmacol202642305440PubTator, text miningPubMed
pH Tunes the DNA Repair Efficiency and Strand Preference of the AlkB Family Enzymes.Chem Res Toxicol202642257680PubTator, text miningPubMed
ALKBH4 confers ferroptosis resistance and drives tumorigenesis via dysregulation of GPX4 in breast cancer cells.In Vitro Cell Dev Biol Anim202642207440PubTator, text miningPubMed
Substrate selectivity of the human RNA m5C methyltransferase NSUN2.Nature202642203868PubTator, text miningPubMed

1 to 10 of 2,913

See all 2,913 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8846

GET https://conductscience.org/api/genes/v1/8846/patents