Gene · 8854
ALDH1A2: aldehyde dehydrogenase 1 family member A2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ALDH1A2: aldehyde dehydrogenase 1 family member A2. Genes, record 8854. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8854
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O94788 | Retinal dehydrogenase 2 | 518 | 7 | Ensembl, GeneID, HGNC |
Source UniProt
Patents16
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 36987 | O94788 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 916 | O94788 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 916 | O94788 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 3831 | O94788 | Espacenet |
| JP 2024178415 A | 2024-12-24 | 8103 | O94788 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 3831 | O94788 | Espacenet |
| JP 2022529532 A | 2022-06-22 | 8103 | O94788 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 106802 | O94788 | Espacenet |
| JP 2022512686 A | 2022-02-07 | 5 | O94788 | Espacenet |
| EP 3863646 A1 | 2021-08-18 | 5 | O94788 | Espacenet |
1 to 10 of 16
See all 16 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,477
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ALDH1A2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| R01HD010808 | Hormonal Regulation Sertoli Cell Maturation | 7 | 2025 |
| R01AA011147 | Ethanol and aldehyde dehydrogenases in health and disease | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 5 | 2025 |
| P30DK017047 | Diabetes Research Center | 4 | 2025 |
| T32CA101642 | Training of Academic Gynecologic Oncologists | 4 | 2025 |
| T32DK007247 | Diabetes, Obesity and Metabolism Training Program | 4 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,477Source NIH's project files
See all 1,477 nih grantsPapers1,746
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Targeting the ALDH-RA Axis with RE-Exo@HA hydrogel to achieve scarless endometrial regeneration and fertility restoration in intrauterine adhesions. | J Control Release | 2026 | 42641931 | PubTator, text mining | PubMed |
| A synergistic deep learning and machine learning framework for screening heterocyclic compounds against ALDH1A1. | Mol Divers | 2026 | 42530797 | PubTator, text mining | PubMed |
| Machine Learning-Guided Multi-Cohort Transcriptomic Profiling Identifies SPON1 and ALDH1A2 as Diagnostic and Prognostic Biomarkers Linked to the Immune Microenvironment in High-Grade Serous Carcinoma. | Int J Mol Sci | 2026 | 42511606 | PubTator, text mining | PubMed |
| The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders. | Brain Pathol | 2026 | 42503643 | PubTator, text mining | PubMed |
| WNT signaling in human pluripotent stem cells promotes HDAC2-dependent epigenetic programs and development of retinoic acid-responsive mesoderm. | Stem Cell Reports | 2026 | 42314670 | PubTator, text mining | PubMed |
| Personalized polygenic profiling based on the genetic architecture of lipid metabolism in the Russian population. | Front Cardiovasc Med | 2026 | 42311766 | PubTator, text mining | PubMed |
| Genome-wide analysis implicates inner ear development in Ménière disease. | Am J Hum Genet | 2026 | 42302782 | PubTator, text mining | PubMed |
| Integrative genomic analysis of 21 orofacial diseases identifies shared genetic architecture with systemic diseases. | Nat Commun | 2026 | 42243103 | PubTator, text mining | PubMed |
| Integrating AI in Medicinal Chemistry for Accelerated Drug Discovery: A Comprehensive SAR (CSAR) Optimization Strategy and Discovery of Potent ALDH3A1 Inhibitors. | J Med Chem | 2026 | 42216908 | PubTator, text mining | PubMed |
| Identification and characterization of a novel aldehyde metabolite of WIN18,446 and associated WIN18,446-ALDH1A2 protein adducts using mass spectrometry. | Drug Metab Rev | 2026 | 42124481 | PubTator, text mining | PubMed |
1 to 10 of 1,746
See all 1,746 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8854
GET https://conductscience.org/api/genes/v1/8854/patents