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NR1I2: nuclear receptor subfamily 1 group I member 2

1 protein, 48 patents, 0 drugs, 0 trials, 4,164 NIH grants and 8,954 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolNR1I2HGNC
Namenuclear receptor subfamily 1 group I member 2HGNC
NCBI Gene ID8856NCBI Gene
HGNC IDHGNC:7968HGNC
EnsemblENSG00000144852NCBI Gene
AliasesBXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXRNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O75469Nuclear receptor subfamily 1 group I member 243480Ensembl, GeneID, HGNCUniProt

Patents 48

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026086503 A2026-05-2682O75469Espacenet
JP 2025147176 A2025-10-0615420O75469Espacenet
EP 4516308 A22025-03-0582O75469Espacenet
JP 2025028160 A2025-02-2815420O75469Espacenet
KR 1020250010750 A2025-01-2115420O75469Espacenet
JP 2024109657 A2024-08-1415259O75469Espacenet
US 11993660 B22024-05-2882O75469Espacenet
JP 2024054208 A2024-04-1682O75469Espacenet
KR 1020240019863 A2024-02-1482O75469Espacenet
JP 2023549761 A2023-11-29370O75469Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4164

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA021765Cancer Center Support Grant (CCSG)652,025NIH's project files
R35GM118041Regulation of xenobiotic receptors PXR and CAR, and CYP3A: implications in drug disposition332,025NIH's project files
ZIABC005708Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers302,025NIH's project files
ZIABC005562Xenobiotic receptors282,025NIH's project files
P30ES007033University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment242,025NIH's project files
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)182,025NIH's project files
P20GM113226Hepatobiology and Toxicology COBRE132,025NIH's project files
P30DK034989Yale Liver Center132,025NIH's project files
P30ES005605Environmental Health Sciences Research Center132,025NIH's project files
T32ES007148Training in Environmental Toxicology132,025NIH's project files

Papers 8954

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825856PubTator, text miningPubMed
42806714PubTator, text miningPubMed
42794816PubTator, text miningPubMed
42794737PubTator, text miningPubMed
42794617PubTator, text miningPubMed
42793293PubTator, text miningPubMed
42777982PubTator, text miningPubMed
42770362PubTator, text miningPubMed
42732815PubTator, text miningPubMed
42710566PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license