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Gene · 8862

APLN: apelin

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. APLN: apelin. Genes, record 8862. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/8862

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
APLN
HGNC
Name
apelin
HGNC
NCBI Gene ID
8862
NCBI Gene
HGNC ID
HGNC:16665
HGNC
Ensembl
ENSG00000171388
NCBI Gene
Aliases
APEL, XNPEP2, apelin
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9ULZ1Apelin775Ensembl, GeneID, HGNC

Source UniProt

Patents112

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026514056 A2026-05-0142Q9ULZ1Espacenet
WO 2026030354 A22026-02-0573Q9ULZ1Espacenet
JP 2026004568 A2026-01-1437641Q9ULZ1Espacenet
KR 1020250169617 A2025-12-0342Q9ULZ1Espacenet
EP 4650780 A22025-11-1912473Q9ULZ1Espacenet
JP 2025147176 A2025-10-06918Q9ULZ1Espacenet
JP 2025529142 A2025-09-045498Q9ULZ1Espacenet
JP 2025527176 A2025-08-201Q9ULZ1Espacenet
US 12371689 B22025-07-295498Q9ULZ1Espacenet
JP 2025517970 A2025-06-1212473Q9ULZ1Espacenet

1 to 10 of 112

See all 112 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,270

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P51OD011104Tulane National Primate Research Center52025
R01HD067449Maternal obesity, AMPK and Developmental Programming52025
P30CA008748Cancer Center Support Grant42025
R01HL124021An endothelial-fibroblast axis connecting senescence to amino acid metabolism for control of vascular stiffness in PAH42025
P20GM109036Tulane COBRE for Clinical and Translational Research in Cardiometabolic Diseases32025
T32HL007227Pathophysiology of Myocardial Disease32025
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition32025
I01BX002042Estrogen Receptor-alpha Effects on Right Ventricular Vascular Density and Angiogenesis in Pulmonary Hypertension22025
K12HD000849Reproductive Scientist Development Program22025
P30AG021332Wake Forest Claude D. Pepper OAIC - Renewal22025

1 to 10 of 1,270Source NIH's project files

See all 1,270 nih grants

Papers4,102

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825352PubTator, text miningPubMed
42783762PubTator, text miningPubMed
42754586PubTator, text miningPubMed
42750037PubTator, text miningPubMed
42735512PubTator, text miningPubMed
42734444PubTator, text miningPubMed
42730193PubTator, text miningPubMed
42706321PubTator, text miningPubMed
42652872PubTator, text miningPubMed
42646269PubTator, text miningPubMed

1 to 10 of 4,102

See all 4,102 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8862

GET https://conductscience.org/api/genes/v1/8862/patents?page=2