Gene · 8863
PER3: period circadian regulator 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PER3: period circadian regulator 3. Genes, record 8863. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8863
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P56645 | Period circadian protein homolog 3 | 1,201 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents17
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2025245188 A2 | 2025-11-27 | 14 | P56645 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7991 | P56645 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7991 | P56645 | Espacenet |
| US 11564998 B2 | 2023-01-31 | 6061 | P56645 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 61963 | P56645 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 164934 | P56645 | Espacenet |
| US 10463751 B2 | 2019-11-05 | 6061 | P56645 | Espacenet |
| JP 2018023373 A | 2018-02-15 | 28788 | P56645 | Espacenet |
| US 9572897 B2 | 2017-02-21 | 6061 | P56645 | Espacenet |
| US 9303079 B2 | 2016-04-05 | 6061 | P56645 | Espacenet |
1 to 10 of 17
See all 17 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,476
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PER3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30CA056036 | Translational Research in Cancer | 5 | 2025 |
| R01NS048471 | Interaction between circadian and sleep circuits | 5 | 2025 |
| R01DK090625 | Integration of Feeding Time and Glucose Metabolism by the Circadian Gene Network | 4 | 2025 |
| R01DK107859 | Genetics of chronotype and impact on metabolic disease | 4 | 2025 |
| T32HL007901 | Training in Sleep, Circadian, and Respiratory Neurobiology | 4 | 2025 |
| P30CA014089 | University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG) | 3 | 2025 |
| P30DK056338 | Texas Medical Center Digestive Diseases Center | 3 | 2025 |
| P30DK072476 | Pennington/Louisiana NORC | 3 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 3 | 2025 |
1 to 10 of 1,476Source NIH's project files
See all 1,476 nih grantsPapers2,066
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| SETDB1 cooperates with the CRL4B complex to promote colorectal cancer tumorigenesis by disrupting circadian rhythm. | Oncogene | 2026 | 42778664 | PubTator, text mining | PubMed |
| Phosphorylation destabilizes Per3 to promote gallbladder carcinoma. | Exp Cell Res | 2026 | 42777803 | PubTator, text mining | PubMed |
| Afternoon exercise was associated with greater fat loss than morning exercise in overweight/obese adults: an exploratory study of PER3 rs228697 genotype matching. | Front Physiol | 2026 | 42597286 | PubTator, text mining | PubMed |
| Exploratory Transcriptomic Profiling of Vein Tissue from Diabetic Patients Undergoing Arteriovenous Fistula Creation for Hemodialysis. | J Atheroscler Thromb | 2026 | 42557021 | PubTator, text mining | PubMed |
| Circadian Disruption as a Determinant of the Tumor Temporal State in Colorectal Cancer: A PRISMA-Based Systematic Review Integrating Metabolism, Immunity, and Metastasis. | Int J Mol Sci | 2026 | 42511510 | PubTator, text mining | PubMed |
| Mathematical mapping of circadian genes in Alzheimer's disease. | Chronobiol Int | 2026 | 42483877 | PubTator, text mining | PubMed |
| Circadian Genotypes in PER3 and Time of Prostate Cancer Radiotherapy Interact to Affect Risk of Late Side Effects. | Clin Cancer Res | 2026 | 42440347 | PubTator, text mining | PubMed |
| Assessing the Association Between Genetic Variants in ACE, SOD1, and PER3 and their Role in Breast Cancer Risk among Jordanian Women. | J Cancer | 2026 | 42327579 | PubTator, text mining | PubMed |
| Machine learning-integrated network toxicology uncovers glioma targets of DEHP. | Front Toxicol | 2026 | 42183337 | PubTator, text mining | PubMed |
| Local ancestry inference identifies robust evidence of selection in Neolithic Europe. | bioRxiv | 2026 | 42094542 | PubTator, text mining | PubMed |
1 to 10 of 2,066
See all 2,066 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8863
GET https://conductscience.org/api/genes/v1/8863/patents