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Gene · 8863

PER3: period circadian regulator 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PER3: period circadian regulator 3. Genes, record 8863. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8863

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Gene

Symbol
PER3
HGNC
Name
period circadian regulator 3
HGNC
NCBI Gene ID
8863
NCBI Gene
HGNC ID
HGNC:8847
HGNC
Ensembl
ENSG00000049246
NCBI Gene
Aliases
FASPS3, GIG13
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P56645Period circadian protein homolog 31,2010Ensembl, GeneID, HGNC

Source UniProt

Patents17

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2025245188 A22025-11-2714P56645Espacenet
EP 4650780 A22025-11-197991P56645Espacenet
JP 2025517970 A2025-06-127991P56645Espacenet
US 11564998 B22023-01-316061P56645Espacenet
US 11446398 B22022-09-2061963P56645Espacenet
JP 2022524081 A2022-04-27164934P56645Espacenet
US 10463751 B22019-11-056061P56645Espacenet
JP 2018023373 A2018-02-1528788P56645Espacenet
US 9572897 B22017-02-216061P56645Espacenet
US 9303079 B22016-04-056061P56645Espacenet

1 to 10 of 17

See all 17 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,476

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePER3 papersNewest fiscal year
P30CA016672Cancer Center Support Grant52025
P30CA056036Translational Research in Cancer52025
R01NS048471Interaction between circadian and sleep circuits52025
R01DK090625Integration of Feeding Time and Glucose Metabolism by the Circadian Gene Network42025
R01DK107859Genetics of chronotype and impact on metabolic disease42025
T32HL007901Training in Sleep, Circadian, and Respiratory Neurobiology42025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)32025
P30DK056338Texas Medical Center Digestive Diseases Center32025
P30DK072476Pennington/Louisiana NORC32025
P30ES013508Center of Excellence in Environmental Toxicology32025

1 to 10 of 1,476Source NIH's project files

See all 1,476 nih grants

Papers2,066

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
SETDB1 cooperates with the CRL4B complex to promote colorectal cancer tumorigenesis by disrupting circadian rhythm.Oncogene202642778664PubTator, text miningPubMed
Phosphorylation destabilizes Per3 to promote gallbladder carcinoma.Exp Cell Res202642777803PubTator, text miningPubMed
Afternoon exercise was associated with greater fat loss than morning exercise in overweight/obese adults: an exploratory study of PER3 rs228697 genotype matching.Front Physiol202642597286PubTator, text miningPubMed
Exploratory Transcriptomic Profiling of Vein Tissue from Diabetic Patients Undergoing Arteriovenous Fistula Creation for Hemodialysis.J Atheroscler Thromb202642557021PubTator, text miningPubMed
Circadian Disruption as a Determinant of the Tumor Temporal State in Colorectal Cancer: A PRISMA-Based Systematic Review Integrating Metabolism, Immunity, and Metastasis.Int J Mol Sci202642511510PubTator, text miningPubMed
Mathematical mapping of circadian genes in Alzheimer's disease.Chronobiol Int202642483877PubTator, text miningPubMed
Circadian Genotypes in PER3 and Time of Prostate Cancer Radiotherapy Interact to Affect Risk of Late Side Effects.Clin Cancer Res202642440347PubTator, text miningPubMed
Assessing the Association Between Genetic Variants in ACE, SOD1, and PER3 and their Role in Breast Cancer Risk among Jordanian Women.J Cancer202642327579PubTator, text miningPubMed
Machine learning-integrated network toxicology uncovers glioma targets of DEHP.Front Toxicol202642183337PubTator, text miningPubMed
Local ancestry inference identifies robust evidence of selection in Neolithic Europe.bioRxiv202642094542PubTator, text miningPubMed

1 to 10 of 2,066

See all 2,066 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8863

GET https://conductscience.org/api/genes/v1/8863/patents