ConductScience.org, home

Library / Genes

SPHK1: sphingosine kinase 1

1 protein, 55 patents, 0 drugs, 0 trials, 2,399 NIH grants and 5,068 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSPHK1HGNC
Namesphingosine kinase 1HGNC
NCBI Gene ID8877NCBI Gene
HGNC IDHGNC:11240HGNC
EnsemblENSG00000176170NCBI Gene
AliasesSPHKNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9NYA1Sphingosine kinase 13845Ensembl, GeneID, HGNCUniProt

Patents 55

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910930Q9NYA1Espacenet
EP 4640849 A22025-10-291666Q9NYA1Espacenet
EP 4641201 A22025-10-2911321Q9NYA1Espacenet
JP 2025519096 A2025-06-241666Q9NYA1Espacenet
JP 2025517969 A2025-06-1211321Q9NYA1Espacenet
JP 2025517970 A2025-06-1210930Q9NYA1Espacenet
JP 2024123008 A2024-09-108519Q9NYA1Espacenet
JP 2024123008 A2024-09-108521Q9NYA1Espacenet
JP 2024123008 A2024-09-108523Q9NYA1Espacenet
US 12037329 B22024-07-161Q9NYA1Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2399

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P01CA097132Sphingolipids in Cancer Biology and Therapy732,025NIH's project files
P30CA016059Massey Cancer Center - Cancer Center Support Grant402,025NIH's project files
P30CA138313Medical University of South Carolina - Cancer Center Support Grant242,025NIH's project files
P30CA016672Cancer Center Support Grant142,025NIH's project files
R01DE016572Ceramide Signaling in the Regulation of Head & Neck Cancer Cell Death and Therapy122,025NIH's project files
P30CA044579University of Virginia Cancer Center Support Grant112,025NIH's project files
P30CA008748Cancer Center Support Grant102,025NIH's project files
R35GM118128Neutral Sphingomyelinases and Bioactive Ceramides102,025NIH's project files
ZIADK056014Mouse Models of Novel Sphingolipid Biology and Disease Mechanisms102,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant92,025NIH's project files

Papers 5068

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42807526PubTator, text miningPubMed
42800384PubTator, text miningPubMed
42763886PubTator, text miningPubMed
42730290PubTator, text miningPubMed
42704675PubTator, text miningPubMed
42605829PubTator, text miningPubMed
42603626PubTator, text miningPubMed
42592470PubTator, text miningPubMed
42584761PubTator, text miningPubMed
42502105PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license