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SQSTM1: sequestosome 1

1 protein, 91 patents, 0 drugs, 0 trials, 5,398 NIH grants and 13,305 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSQSTM1HGNC
Namesequestosome 1HGNC
NCBI Gene ID8878NCBI Gene
HGNC IDHGNC:11280HGNC
EnsemblENSG00000161011NCBI Gene
AliasesA170, DMRV, EBIAP, FTDALS3, NADGP, OSIL, PDB3, ZIP3, p60, p62, p62BNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q13501Sequestosome-144026Ensembl, GeneID, HGNCUniProt

Patents 91

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12618845 B22026-05-0529Q13501Espacenet
JP 2026065001 A2026-04-14123Q13501Espacenet
EP 4692367 A12026-02-115Q13501Espacenet
JP 2026004568 A2026-01-1463010Q13501Espacenet
KR 1020250169534 A2025-12-035Q13501Espacenet
EP 4650780 A22025-11-1910707Q13501Espacenet
EP 4618968 A12025-09-2429Q13501Espacenet
JP 2025517970 A2025-06-1210707Q13501Espacenet
JP 2025074818 A2025-05-142Q13501Espacenet
JP 2025062601 A2025-04-1491Q13501Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5398

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant412,025NIH's project files
P30CA008748Cancer Center Support Grant242,025NIH's project files
R35GM131919The mechanism and regulation of autophagy232,025NIH's project files
P30ES006694Southwest Environmental Health Sciences Center222,025NIH's project files
R01CA126792Autophagy and Pro-metastatic Differentiation202,025NIH's project files
P30CA016059Massey Cancer Center - Cancer Center Support Grant162,025NIH's project files
P30CA030199Cancer Center Support Grant (CCSG)162,025NIH's project files
P30CA047904Cancer Center Support Grant162,025NIH's project files
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital162,025NIH's project files
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions132,025NIH's project files

Papers 13305

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824422PubTator, text miningPubMed
42819416PubTator, text miningPubMed
42817668PubTator, text miningPubMed
42817119PubTator, text miningPubMed
42803966PubTator, text miningPubMed
42802668PubTator, text miningPubMed
42798015PubTator, text miningPubMed
42797498PubTator, text miningPubMed
42778546PubTator, text miningPubMed
42769438PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license