Gene · 8915
BCL10: BCL10 immune signaling adaptor
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. BCL10: BCL10 immune signaling adaptor. Genes, record 8915. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8915
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O95999 | B-cell lymphoma/leukemia 10 | 233 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents45
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 38651 | O95999 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 38652 | O95999 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 19685 | O95999 | Espacenet |
| JP 2025524002 A | 2025-07-25 | 12 | O95999 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 19685 | O95999 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 8433 | O95999 | Espacenet |
| KR 1020250039465 A | 2025-03-20 | 12 | O95999 | Espacenet |
| JP 2024023699 A | 2024-02-21 | 12 | O95999 | Espacenet |
| JP 2024505890 A | 2024-02-08 | 12 | O95999 | Espacenet |
| US 11879000 B2 | 2024-01-23 | 2 | O95999 | Espacenet |
1 to 10 of 45
See all 45 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,639
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | BCL10 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 16 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 12 | 2025 |
| ZIABC011008 | Oncogenic mechanisms and molecular targets in lymphoma | 12 | 2025 |
| P30DK040561 | Boston Area Nutrition Obesity Research Center (NORC) | 6 | 2025 |
| R01AI127564 | Genome-wide search for inborn errors of IL-17 immunity underlying chronic mucocutaneous candidiasis | 6 | 2025 |
| T32HL007622 | Boxer Training Program in Hematology | 6 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 5 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 5 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 5 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 1,639Source NIH's project files
See all 1,639 nih grantsPapers2,643
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Running on Empty Signals: What Human MALT1 Deficiency Reveals About Immune Control. | J Immunol Res | 2026 | 42745540 | PubTator, text mining | PubMed |
| Complex landscape of somatic copy number alterations in head and neck paragangliomas. | Front Endocrinol (Lausanne) | 2026 | 42666236 | PubTator, text mining | PubMed |
| Systems pharmacology reveals type I interferon and myeloid-like B cell reprogramming as candidate druggable axes in antiphospholipid syndrome. | PLoS One | 2026 | 42647509 | PubTator, text mining | PubMed |
| Beyond Infection: Mitochondrial Reprogramming and Immunometabolic Adaptation in Helicobacter pylori-Associated Gastric MALT Lymphoma. | Diseases | 2026 | 42645088 | PubTator, text mining | PubMed |
| Case Report: Pancreatic amphicrine-like carcinoma with acinar differentiation harboring a KANK4-RAF1 gene fusion. | Pathol Oncol Res | 2026 | 42643275 | PubTator, text mining | PubMed |
| A role for the protease MALT1 in EBV-mediated B-cell transformation by Latent Membrane Proteins 1 and 2. | Leukemia | 2026 | 42595846 | PubTator, text mining | PubMed |
| The requirement of MALT1 activity for the growth of adult T cell leukemia/lymphoma. | iScience | 2026 | 42542590 | PubTator, text mining | PubMed |
| GutMGene-Guided Peripheral Blood Transcriptomics Identifies an FLNA-Associated Host-Gene Signal in Diabetic Retinopathy. | Int J Mol Sci | 2026 | 42511525 | PubTator, text mining | PubMed |
| A novel linker region truncating variant in BCL10 underlies a leaky immunodeficiency phenotype. | Pediatr Allergy Immunol | 2026 | 42473108 | PubTator, text mining | PubMed |
| Integrating Methylation Signature Modifications and Subtype Classification into a Prognostic Risk Model for Survival Prognosis and Predicting Immunotherapy Response in Colorectal Cancer. | Curr Med Chem | 2026 | 42458941 | PubTator, text mining | PubMed |
1 to 10 of 2,643
See all 2,643 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8915
GET https://conductscience.org/api/genes/v1/8915/patents?page=2