Gene · 8932
MBD2: methyl-CpG binding domain protein 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MBD2: methyl-CpG binding domain protein 2. Genes, record 8932. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8932
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UBB5 | Methyl-CpG-binding domain protein 2 | 411 | 14 | Ensembl, GeneID, HGNC |
Source UniProt
Patents42
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4698657 A2 | 2026-02-25 | 385 | Q9UBB5 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 53374 | Q9UBB5 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15265 | Q9UBB5 | Espacenet |
| JP 2025509420 A | 2025-04-11 | 5 | Q9UBB5 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15265 | Q9UBB5 | Espacenet |
| EP 4493713 A2 | 2025-01-22 | 5 | Q9UBB5 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15265 | Q9UBB5 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15104 | Q9UBB5 | Espacenet |
| US 11920164 B2 | 2024-03-05 | 6 | Q9UBB5 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 50861 | Q9UBB5 | Espacenet |
1 to 10 of 42
See all 42 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,946
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MBD2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 14 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 12 | 2025 |
| P30CA016059 | Massey Cancer Center - Cancer Center Support Grant | 12 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 9 | 2025 |
| ZIAES101965 | Eukaryotic Transcriptional Regulation | 9 | 2025 |
| P30CA022453 | CANCER CENTER SUPPORT GRANT | 8 | 2025 |
| R01DK115563 | The Role of the MBD2-NuRD Complex in Gamma-Globin Gene Silencing | 7 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 6 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 1,946Source NIH's project files
See all 1,946 nih grantsPapers2,613
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Extracellular Vesicles in Cardiovascular Disease: Intercellular Signaling, Liquid Biopsy Biomarkers, and Therapeutic Translation. | Circ Res | 2026 | 42594169 | PubTator, text mining | PubMed |
| Structure-guided targeting of the GATAD2A-CHD4 interaction within the MBD2-NuRD complex results in high levels of HbF in adult erythroid cells. | bioRxiv | 2026 | 42539289 | PubTator, text mining | PubMed |
| Histone Methylation and Chromatin Remodeling in Non-Small Cell Lung Cancer: Mechanisms of Oncogenesis and Emerging Therapeutic Strategies. | Biomedicines | 2026 | 42512002 | PubTator, text mining | PubMed |
| HBx-Associated Reactivation of the IGF2 Locus in Chronic HBV Infection and HBV-Related Hepatocarcinogenesis: Evidence Boundaries and Biomarker Implications. | Biomedicines | 2026 | 42511915 | PubTator, text mining | PubMed |
| Exercise, Demethylase FTO, Neurological Disorders, and Neuropathic Pain: Potential Molecular Mechanisms. | CNS Neurosci Ther | 2026 | 42504920 | PubTator, text mining | PubMed |
| Targeted Transcriptional Repression by Induced Proximity. | ACS Cent Sci | 2026 | 42500035 | PubTator, text mining | PubMed |
| Overcoming Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma (HNSCC): The Role of Histone Methyltransferase and Demethylase Inhibitors. | Cancers (Basel) | 2026 | 42449712 | PubTator, text mining | PubMed |
| Development of a prognostic prediction model incorporating KDM1B for esophageal squamous cell carcinoma: an integrated transcriptomic and functional analysis. | J Gastrointest Oncol | 2026 | 42434278 | PubTator, text mining | PubMed |
| A potent small-chemical MBD2 inhibitor, KCC-07, induces selective cytotoxicity in hepatocellular and prostate cancer cells. | Mol Biol Rep | 2026 | 42429995 | PubTator, text mining | PubMed |
| Epigenetic regulation of cardiac physiology and pathophysiology: biological sex matters. | J Cardiovasc Aging | 2026 | 42369572 | PubTator, text mining | PubMed |
1 to 10 of 2,613
See all 2,613 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8932
GET https://conductscience.org/api/genes/v1/8932/patents?page=2