Gene · 8972
MGAM: maltase-glucoamylase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MGAM: maltase-glucoamylase. Genes, record 8972. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8972
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O43451 | Maltase-glucoamylase | 2,753 | 12 | Ensembl, GeneID, HGNC |
Source UniProt
Patents4
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
Drugs4
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials82
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07122102 | ACARBOSE | ClinicalTrials.gov | ||
| NCT07074379 | ACARBOSE | ClinicalTrials.gov | ||
| NCT06993428 | ACARBOSE | PHASE2 | ClinicalTrials.gov | |
| NCT05934110 | ACARBOSE | PHASE2 | ClinicalTrials.gov | |
| NCT05688332 | VOGLIBOSE | PHASE3 | ClinicalTrials.gov | |
| NCT05629806 | ACARBOSE | PHASE3 | ClinicalTrials.gov | |
| NCT05487859 | ACARBOSE | PHASE2 | ClinicalTrials.gov | |
| NCT05261997 | ACARBOSE | ClinicalTrials.gov | ||
| NCT05035849 | ACARBOSE | ClinicalTrials.gov | ||
| NCT04665570 | ACARBOSE | ClinicalTrials.gov |
1 to 10 of 82
See all 82 trialsNIH grants347
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MGAM papers | Newest fiscal year |
|---|---|---|---|
| R01DK067859 | Development of Assays for Newborn Screening and for Post-Screening Evaluation of Disease Severity | 7 | 2025 |
| P30DK056338 | Texas Medical Center Digestive Diseases Center | 5 | 2025 |
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 2 | 2025 |
| T32HL007024 | Cardiovascular Epidemiology Institutional Training | 2 | 2025 |
| K12HD000849 | Reproductive Scientist Development Program | 1 | 2025 |
| P20GM103408 | Idaho INBRE Program | 1 | 2025 |
| P20GM103440 | Nevada IDeA Networks of Biomedical Research Excellence (INBRE) | 1 | 2025 |
| P30AG028740 | University of Florida Older Americans Independence Center (OAIC) | 1 | 2025 |
| P30AG062421 | Massachusetts Alzheimer's Disease Research Center (MADRC) | 1 | 2025 |
| P30AG062422 | New Approaches to Dementia Heterogeneity | 1 | 2025 |
1 to 10 of 347Source NIH's project files
See all 347 nih grantsPapers645
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Metabolomics-Based Identification of α-Glucosidase Inhibitors from Pometia pinnata Stem Bark Using LC-HRMS and Molecular Docking. | Molecules | 2026 | 42796519 | PubTator, text mining | PubMed |
| Synthesis and Antidiabetic Evaluation of Novel 2,4-Thiazolidinedione Derivatives Targeting Key Carbohydrate-Digesting Enzymes. | Molecules | 2026 | 42796447 | PubTator, text mining | PubMed |
| Computer-Aided Design of Novel Acrylamido Derivatives as Potential Oral Antidiabetic Agents. | Med Chem | 2026 | 42736679 | PubTator, text mining | PubMed |
| Unraveling the Synergistic Inhibition of Human Maltase-Glucoamylase by Baicalein and Acarbose: Integrated Pharmacodynamics and Computational Insights. | Pharmaceuticals (Basel) | 2026 | 42653712 | PubTator, text mining | PubMed |
| Generative AI-augmented transcriptomic and microbiome analysis across inflammatory and fibrotic disease states in Crohn's disease. | Front Artif Intell | 2026 | 42614810 | PubTator, text mining | PubMed |
| Design, synthesis, and biological evaluation of p-thymol-derived 1,2,4-triazole sulfonyl hydrazides as potent α-amylase and α-glucosidase inhiabitors: molecular docking and ADME insights. | In Silico Pharmacol | 2026 | 42389728 | PubTator, text mining | PubMed |
| Construction and validation of a diagnostic model for Kawasaki disease based on neutrophil-related genes and analysis of immune infiltration. | Transl Pediatr | 2026 | 42292614 | PubTator, text mining | PubMed |
| Neutrophil extracellular traps-related biomarkers in idiopathic pulmonary arterial hypertension: A machine learning-based identification and experimental validation study. | Mol Immunol | 2026 | 42085826 | PubTator, text mining | PubMed |
| Alpha-Glucosidase inhibitory activity and molecular docking analysis of a new biflavan isolated from Impatiens macrantha. | Nat Prod Res | 2026 | 42059829 | PubTator, text mining | PubMed |
| TAS2R38 taster variants-linked MGAM expression in Alzheimer's disease: a novel target for precision drug repurposing. | Front Aging Neurosci | 2026 | 41858791 | PubTator, text mining | PubMed |
1 to 10 of 645
See all 645 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8972
GET https://conductscience.org/api/genes/v1/8972/trials?page=2