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Gene · 8972

MGAM: maltase-glucoamylase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MGAM: maltase-glucoamylase. Genes, record 8972. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8972

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Gene

Symbol
MGAM
HGNC
Name
maltase-glucoamylase
HGNC
NCBI Gene ID
8972
NCBI Gene
HGNC ID
HGNC:7043
HGNC
Ensembl
ENSG00000257335
NCBI Gene
Aliases
MG, MGA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O43451Maltase-glucoamylase2,75312Ensembl, GeneID, HGNC

Source UniProt

Patents4

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-2916442O43451Espacenet
JP 2025517969 A2025-06-1216442O43451Espacenet
US 11446398 B22022-09-2048932O43451Espacenet
JP 2022524081 A2022-04-27151903O43451Espacenet

Drugs4

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ACARBOSECHEMBL404271Maltase-glucoamylase inhibitorINHIBITORChEMBL
CELGOSIVIRCHEMBL2110737Alpha glucosidase inhibitorINHIBITORChEMBL
MIGLITOLCHEMBL1561Maltase-glucoamylase inhibitorINHIBITORChEMBL
VOGLIBOSECHEMBL476960Alpha glucosidase inhibitorINHIBITORChEMBL

Trials82

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants347

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMGAM papersNewest fiscal year
R01DK067859Development of Assays for Newborn Screening and for Post-Screening Evaluation of Disease Severity72025
P30DK056338Texas Medical Center Digestive Diseases Center52025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease22025
T32HL007024Cardiovascular Epidemiology Institutional Training22025
K12HD000849Reproductive Scientist Development Program12025
P20GM103408Idaho INBRE Program12025
P20GM103440Nevada IDeA Networks of Biomedical Research Excellence (INBRE)12025
P30AG028740University of Florida Older Americans Independence Center (OAIC)12025
P30AG062421Massachusetts Alzheimer's Disease Research Center (MADRC)12025
P30AG062422New Approaches to Dementia Heterogeneity12025

1 to 10 of 347Source NIH's project files

See all 347 nih grants

Papers645

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Metabolomics-Based Identification of α-Glucosidase Inhibitors from Pometia pinnata Stem Bark Using LC-HRMS and Molecular Docking.Molecules202642796519PubTator, text miningPubMed
Synthesis and Antidiabetic Evaluation of Novel 2,4-Thiazolidinedione Derivatives Targeting Key Carbohydrate-Digesting Enzymes.Molecules202642796447PubTator, text miningPubMed
Computer-Aided Design of Novel Acrylamido Derivatives as Potential Oral Antidiabetic Agents.Med Chem202642736679PubTator, text miningPubMed
Unraveling the Synergistic Inhibition of Human Maltase-Glucoamylase by Baicalein and Acarbose: Integrated Pharmacodynamics and Computational Insights.Pharmaceuticals (Basel)202642653712PubTator, text miningPubMed
Generative AI-augmented transcriptomic and microbiome analysis across inflammatory and fibrotic disease states in Crohn's disease.Front Artif Intell202642614810PubTator, text miningPubMed
Design, synthesis, and biological evaluation of p-thymol-derived 1,2,4-triazole sulfonyl hydrazides as potent α-amylase and α-glucosidase inhiabitors: molecular docking and ADME insights.In Silico Pharmacol202642389728PubTator, text miningPubMed
Construction and validation of a diagnostic model for Kawasaki disease based on neutrophil-related genes and analysis of immune infiltration.Transl Pediatr202642292614PubTator, text miningPubMed
Neutrophil extracellular traps-related biomarkers in idiopathic pulmonary arterial hypertension: A machine learning-based identification and experimental validation study.Mol Immunol202642085826PubTator, text miningPubMed
Alpha-Glucosidase inhibitory activity and molecular docking analysis of a new biflavan isolated from Impatiens macrantha.Nat Prod Res202642059829PubTator, text miningPubMed
TAS2R38 taster variants-linked MGAM expression in Alzheimer's disease: a novel target for precision drug repurposing.Front Aging Neurosci202641858791PubTator, text miningPubMed

1 to 10 of 645

See all 645 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/8972

GET https://conductscience.org/api/genes/v1/8972/trials?page=2