Gene · 8976
WASL: WASP like actin nucleation promoting factor
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. WASL: WASP like actin nucleation promoting factor. Genes, record 8976. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/8976
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O00401 | Actin nucleation-promoting factor WASL | 505 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents23
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 579 | O00401 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 408 | O00401 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 408 | O00401 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 579 | O00401 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 9087 | O00401 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 97753 | O00401 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 200724 | O00401 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 12555 | O00401 | Espacenet |
| US 10501513 B2 | 2019-12-10 | 9087 | O00401 | Espacenet |
| JP 2017197545 A | 2017-11-02 | 33788 | O00401 | Espacenet |
1 to 10 of 23
See all 23 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,726
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | WASL papers | Newest fiscal year |
|---|---|---|---|
| R01GM073791 | Structural-Functional Basis of Actin Cytoskeleton Dynamics | 15 | 2025 |
| P30CA013330 | Cancer Center Support Grant | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| R35GM118149 | Actin assembly and clathrin-mediated endocytosis in yeast and mammals | 6 | 2025 |
| ZIACL080017 | IQGAP1 in tumorigenesis | 6 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 5 | 2025 |
| P30DA018343 | Yale/NIDA Neuroproteomics Center | 5 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 5 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 5 | 2025 |
1 to 10 of 1,726Source NIH's project files
See all 1,726 nih grantsPapers2,524
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A novel minimally invasive diagnostic approach of various brain malignancies based on differential miRNA expression. | J Neurooncol | 2026 | 42809056 | PubTator, text mining | PubMed |
| miR-185 influences Cdc42-N-WASP signaling pathway in gastric cancer by targeting CTTN. | Pak J Pharm Sci | 2026 | 42632930 | PubTator, text mining | PubMed |
| The Nance-Horan syndrome protein NHS regulates cell migration persistence by organizing WAVE and N-WASP nucleation-promoting factor complexes. | J Biol Chem | 2026 | 42595116 | PubTator, text mining | PubMed |
| Microscale matrix defects suppress tension-dependent protrusions and stall collective cell migration. | Cell Rep | 2026 | 42537646 | PubTator, text mining | PubMed |
| PAK4 in the Tumor Immune Microenvironment: Biological Functions, Regulatory Mechanisms, and Targeted Therapeutic Strategies. | Med Res Rev | 2026 | 42489806 | PubTator, text mining | PubMed |
| The mechanisms of DEPDC7-mediated actin cap establishment and meiosis progression in oocytes. | EMBO Rep | 2026 | 42332067 | PubTator, text mining | PubMed |
| Molecular and functional consequences of the Cdc42 C81Y mutation in immune-associated malignancy. | Arch Biochem Biophys | 2026 | 42173300 | PubTator, text mining | PubMed |
| N-WASP is downregulated in patients with acute myeloid leukemia (AML) and is associated with poor prognosis. | Sci Rep | 2026 | 42014831 | PubTator, text mining | PubMed |
| DYRK1A and Parkinson's disease, facts and hypotheses. | Neurobiol Dis | 2026 | 41991085 | PubTator, text mining | PubMed |
| Dispensable players: N-WASP and WASP are not crucial for homology-directed DNA repair. | EMBO Rep | 2026 | 41963733 | PubTator, text mining | PubMed |
1 to 10 of 2,524
See all 2,524 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/8976
GET https://conductscience.org/api/genes/v1/8976/patents?page=2