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Gene · 9002

Papers2,206

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The Structural Analogy of MASP-2 with Thrombin and MASP-1 Reveals Strong Binding with PAR4.Antiinflamm Antiallergy Agents Med Chem202641588767PubTator, text miningPubMed
Computational analysis of the structural and functional impact of the deleterious nsSNPs in the human F2R gene and their implications in glioma.Biochem Biophys Rep202641550510PubTator, text miningPubMed
Can drug-induced platelet dysfunction be reversed?Res Pract Thromb Haemost202641541607PubTator, text miningPubMed
Protease-Activated Receptor 4 (PAR4)-Tethered Ligand Antagonists Demonstrate Thrombin Liability.ACS Pharmacol Transl Sci202641536282PubTator, text miningPubMed
Neutrophil cathepsin G potentiates biased signaling through protease-activated receptor 4.Blood Adv202641370205PubTator, text miningPubMed
DENetwork unveils non-differentially expressed genes with functional relevance across conditions through information flow perturbation.Nucleic Acids Res202541404797PubTator, text miningPubMed
Trypsin Activates Human Platelets via Proteolytic Cleavage of Protease-Activated Receptor 4.Thromb Haemost202541248893PubTator, text miningPubMed
Mechanisms of Thromboinflammation in Viral Infections-A Narrative Review.Viruses202541012635PubTator, text miningPubMed
Curcumin Inhibits Protease Activated Receptor 2-Induced ERK Phosphorylation Calcium Mobilization and Anti-Apoptotic Signaling in Inflammation-Driven Colorectal Cancer Cells.Cells202541002416PubTator, text miningPubMed
The role of protease-activated receptors (PARs) in the functioning of platelets and platelet-derived microparticles (PMPs).Front Mol Biosci202540994550PubTator, text miningPubMed
Transient ligand contacts of the intrinsically disordered N-terminus of neuropeptide Y2 receptor regulate arrestin-3 recruitment.Nat Commun202540973726PubTator, text miningPubMed
Platelet protease-activated receptor 4 genotype and response to aspirin in pregnancy.Blood Vessel Thromb Hemost202540918740PubTator, text miningPubMed
Immune-coagulation dynamics in severe COVID-19 revealed by autoantibody profiling and multi-omics integration.Sci Rep202540890263PubTator, text miningPubMed
DNA methylation-based health predictors: advances, applications, and perspectives.Epigenomics202540856171PubTator, text miningPubMed
Pattern recognition receptor-associated immuno-thrombotic transcript changes in platelets and leukocytes with COVID19.PLoS Pathog202540825056PubTator, text miningPubMed
The protease-activated receptors are expressed in glioblastoma and differentially modulate adherent versus stem-like growth of LN-18 GBM cells.Front Oncol202540766339PubTator, text miningPubMed
Oxidative damage, genetic and epigenetic alterations in hexavalent chromium exposed workers - A cross-sectional study within the SafeChrom project.Environ Res202540516896PubTator, text miningPubMed
A Five-Gene Signature for the Prediction of Event-Free Survival of Both Pediatric and Adult Acute Myeloid Leukemia.Diagnostics (Basel)202540506993PubTator, text miningPubMed
7,4'-dimethoxy-3-hydroxyflavone, a protease-activated receptor 4 (PAR4) inhibitor with antioxidant activity, ameliorates diabetic endothelial dysfunction.Br J Pharmacol202540501374PubTator, text miningPubMed
Platelets and diseases: signal transduction and advances in targeted therapy.Signal Transduct Target Ther202540374650PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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