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Gene · 9045

RPL14: ribosomal protein L14

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RPL14: ribosomal protein L14. Genes, record 9045. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9045

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Gene

Symbol
RPL14
HGNC
Name
ribosomal protein L14
HGNC
NCBI Gene ID
9045
NCBI Gene
HGNC ID
HGNC:10305
HGNC
Ensembl
ENSG00000188846
NCBI Gene
Aliases
CAG-ISL-7, CTG-B33, L14, RL14, eL14, hRL14
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P50914Large ribosomal subunit protein eL14215176Ensembl, GeneID, HGNC

Source UniProt

Patents26

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1911365P50914Espacenet
EP 4650780 A22025-11-196949P50914Espacenet
JP 2025517970 A2025-06-126949P50914Espacenet
JP 2025517970 A2025-06-1211365P50914Espacenet
US 11564998 B22023-01-315677P50914Espacenet
US 11564998 B22023-01-316937P50914Espacenet
US 11446398 B22022-09-2073947P50914Espacenet
US 11446398 B22022-09-2073948P50914Espacenet
JP 2022524081 A2022-04-27176918P50914Espacenet
JP 2022524081 A2022-04-27176919P50914Espacenet

1 to 10 of 26

See all 26 patents

Drugs9

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ATALURENCHEMBL25699780S Ribosome modulatorMODULATORChEMBL
CITATUZUMAB BOGATOXCHEMBL174300080S Ribosome inhibitorINHIBITORChEMBL
CYCLOHEXIMIDECHEMBL12329280S Ribosome inhibitorINHIBITORChEMBL
DORLIMOMAB ARITOXCHEMBL210912480S Ribosome inhibitorINHIBITORChEMBL
ELX-02CHEMBL429774480S Ribosome modulatorMODULATORChEMBL
MT-3724CHEMBL429778980S Ribosome inhibitorINHIBITORChEMBL
TAPLITUMOMAB PAPTOXCHEMBL210789080S Ribosome inhibitorINHIBITORChEMBL
TELIMOMAB ARITOXCHEMBL210879080S Ribosome inhibitorINHIBITORChEMBL
ZOLIMOMAB ARITOXCHEMBL210878580S Ribosome inhibitorINHIBITORChEMBL

Trials38

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07523581ELX-02PHASE2ClinicalTrials.gov
NCT05448755ELX-02PHASE22026-02-24ClinicalTrials.gov
NCT04336826ATALURENPHASE22024-04-01ClinicalTrials.gov
NCT04135495ELX-02PHASE2ClinicalTrials.gov
NCT04126473ELX-02PHASE2ClinicalTrials.gov
NCT04117880ATALURENPHASE2ClinicalTrials.gov
NCT04069260ELX-02PHASE2ClinicalTrials.gov
NCT04014530ATALURENPHASE1/PHASE2ClinicalTrials.gov
NCT03796637ATALURENPHASE22022-04-05ClinicalTrials.gov
NCT03645395MT-3724PHASE22022-08-16ClinicalTrials.gov

1 to 10 of 38

See all 38 trials

NIH grants542

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRPL14 papersNewest fiscal year
P30CA068485Cancer Center Support Grant62025
R01CA200709Facilitated recruitment of MYC to chromatin by interaction with WDR562025
P30DK058404Molecular and Cellular Basis for Digestive Diseases42025
P30EY008126Core Grant in Vision Research42025
T32CA119925Integrated Biological Systems Training in Oncology42025
P50CA236733Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal Cancer32025
T32CA217834VOLT (Vanderbilt Oncology Training Program)32025
P01CA092584Structural Cell Biology of DNA Repair Machines22025
P30AI027763UCSF-Bay Area Center for AIDS Research22025
P30CA016058Cancer Center Support Grant22025

1 to 10 of 542Source NIH's project files

See all 542 nih grants

Papers808

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Plasma proteome-genome integration reveals novel protein biomarkers and therapeutic targets linked to breast cancer survival.Arch Med Sci202642540540PubTator, text miningPubMed
The Helicobacter pylori ribosomal silencing factor RsfS is required for low-growth states and chronic infection.bioRxiv202641929121PubTator, text miningPubMed
Nucleolus as a cornerstone linking proliferation and metabolism to cellular responses to stress: involvement of transcription factors MYC and p53.Front Mol Biosci202641777667PubTator, text miningPubMed
RNAseq-based meta-analyses revealed tumor suppressor-inducer fusion events in liver, oral, and ovarian cancer in the Indian population: a cancer cell surviving mechanism.Nucleosides Nucleotides Nucleic Acids202641661231PubTator, text miningPubMed
Lactylation Plays a Novel Role in the Tumor Microenvironment and its Prognostic Implications for Breast Cancer.Recent Pat Anticancer Drug Discov202641582583PubTator, text miningPubMed
Design and in-silico evaluation of PNA-based novel pronucleotide analogues targeting RNA-dependent RNA polymerase to combat COVID-19.J Biomol Struct Dyn202639937582PubTator, text miningPubMed
Gene Regulation in Comorbid Migraine and Myogenic Temporomandibular Disorder Pain.Genes (Basel)202541465107PubTator, text miningPubMed
Extracellular vesicles for macrophage reprogramming: an emerging paradigm in immunomodulatory therapeutics.J Biol Eng202541430279PubTator, text miningPubMed
Decoding immune-metabolic crosstalk in ARDS: a transcriptomic exploration of biomarkers, cellular dynamics, and therapeutic pathways.Front Immunol202541221285PubTator, text miningPubMed
LTO1 and YAE1 regulate MHC-I expression via nonsense-mediated RNA decay in tumor cells.J Immunother Cancer202540987494PubTator, text miningPubMed

1 to 10 of 808

See all 808 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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