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Gene · 9098

USP6: ubiquitin specific peptidase 6

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. USP6: ubiquitin specific peptidase 6. Genes, record 9098. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9098

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Gene

Symbol
USP6
HGNC
Name
ubiquitin specific peptidase 6
HGNC
NCBI Gene ID
9098
NCBI Gene
HGNC ID
HGNC:12629
HGNC
Ensembl
ENSG00000129204
NCBI Gene
Aliases
HRP1, TRE17, TRE2, TRESMCR, Tre-2, Tre2, USP6-short
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P35125Ubiquitin carboxyl-terminal hydrolase 61,4060Ensembl, GeneID, HGNC

Source UniProt

Patents23

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1469018P35125Espacenet
EP 4641201 A22025-10-29926P35125Espacenet
JP 2025517969 A2025-06-12926P35125Espacenet
JP 2023551068 A2023-12-0655P35125Espacenet
JP 2023549761 A2023-11-2955P35125Espacenet
JP 2023549167 A2023-11-2255P35125Espacenet
JP 2023548973 A2023-11-2155P35125Espacenet
US 11686014 B22023-06-2712P35125Espacenet
US 11446398 B22022-09-2095030P35125Espacenet
US 11446398 B22022-09-2095031P35125Espacenet

1 to 10 of 23

See all 23 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants627

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUSP6 papersNewest fiscal year
P30CA008748Cancer Center Support Grant72025
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes32025
P30DK036836Diabetes Research Center32025
R01HG002385Long-read sequence and assembly of segmental duplications32025
R35GM130207Chemical Approaches to Control the Function of Regulatory RNAs32025
P30CA016086Cancer Center Support Grant22025
P30CA016520Abramson Cancer Center Support Grant22025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant22025
P30CA023108Cancer Center Support Grant22025
P30CA036727Buffett Cancer Center Support Grant22025

1 to 10 of 627Source NIH's project files

See all 627 nih grants

Papers1,292

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Successful Denosumab Treatment of a Pediatric Spinal Aneurysmal Bone Cyst With COL1A1-USP6 Rearrangement Histologically Mimicking Giant Cell Tumor of Bone.Pediatr Blood Cancer202642742538PubTator, text miningPubMed
USP6-FISH Negative Nodular Fasciitis: Benign Impostor of the Orbit.Ophthalmic Plast Reconstr Surg202642727019PubTator, text miningPubMed
Recurrent Fibro-Osseous Pseudotumour of the Digit Mimicking Infection: A Narrative Review and Case Report.Hand (N Y)202642695356PubTator, text miningPubMed
An Update on Selected Giant Cell-Rich Tumors of Soft Tissue.Cancer Genomics Proteomics202642674819PubTator, text miningPubMed
Clival Aneurysmal Bone Cyst With Cavernous Sinus Extension: A Diagnostic Challenge.Cureus202642662863PubTator, text miningPubMed
Management of aneurysmal bone cysts of the spine and sacrum: A narrative review.J Craniovertebr Junction Spine202642643969PubTator, text miningPubMed
Xanthogranulomatous epithelial tumour of the calcaneus in a 32-year-old female: a rare entity.Skeletal Radiol202642552430PubTator, text miningPubMed
USP6 RNA Chromogenic In Situ Hybridization Is Useful in the Diagnosis of Nodular Fasciitis and Aneurysmal Bone Cyst.Mod Pathol202642508574PubTator, text miningPubMed
Update on the molecular pathology of the distinctive giant cell, fibro-osseous and bone forming lesions of the jaws.Semin Diagn Pathol202642361776PubTator, text miningPubMed
Nodular Fasciitis of the Piriformis Muscle Initially Concerning for Metastasis in a Patient With Previous History of Colon Adenocarcinoma: A Case Report.Case Rep Orthop202642282863PubTator, text miningPubMed

1 to 10 of 1,292

See all 1,292 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9098

GET https://conductscience.org/api/genes/v1/9098/patents?page=2