Gene · 91
ACVR1B: activin A receptor type 1B
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ACVR1B: activin A receptor type 1B. Genes, record 91. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/91
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P36896 | Activin receptor type-1B | 505 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents89
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026062645 A | 2026-04-10 | 251 | P36896 | Espacenet |
| JP 2026026172 A | 2026-02-16 | 100 | P36896 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 36234 | P36896 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1661 | P36896 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1267 | P36896 | Espacenet |
| US 12421295 B2 | 2025-09-23 | 26 | P36896 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 256 | P36896 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 256 | P36896 | Espacenet |
| US 12343378 B2 | 2025-07-01 | 100 | P36896 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1267 | P36896 | Espacenet |
1 to 10 of 89
See all 89 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,351
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ACVR1B papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 8 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 6 | 2025 |
| P01AI127335 | Human Cytomegalovirus dysregulation of host hematopoietic progenitor cell signaling pathways to modulate latency and reactivation | 5 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 5 | 2025 |
| P30CA030199 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
| P30CA054174 | Mays Cancer Center at UT Health SA | 4 | 2025 |
| R01HD032067 | Transforming growth factor β family signaling pathways in ovarian and uterine biology | 4 | 2025 |
| T32CA009592 | Microenvironmental Influences in Cancer | 4 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 3 | 2025 |
1 to 10 of 1,351Source NIH's project files
See all 1,351 nih grantsPapers1,784
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Targeting TGFBR1 with the Investigational Inhibitor TP-6379 Improves Hematopoiesis in Low-Risk MDS Ex Vivo. | Cells | 2026 | 42782774 | PubTator, text mining | PubMed |
| Productive Mayaro Virus Infection Requires Host Fatty Acid Synthase for nsP1 S-palmitoylation. | bioRxiv | 2026 | 42539173 | PubTator, text mining | PubMed |
| Upregulation of HIF1A /miR-210 and downregulation of miR-383 in EOPE, IUGR, and EOPE/IUGR: Integrative bioinformatics insights into miR-383 targets. | Placenta | 2026 | 42424821 | PubTator, text mining | PubMed |
| Growth differentiation factor 11 (GDF11) signaling in neural stem cell regulation: molecular and cellular insights. | Rev Neurosci | 2026 | 42299745 | PubTator, text mining | PubMed |
| An integrative mutational and network analysis of pancreatic cancer reveals key genes, and signalling pathways. | Funct Integr Genomics | 2026 | 42277390 | PubTator, text mining | PubMed |
| Activin A in the central nervous system: Mechanistic and therapeutic insights unveiled by emerging technologies. | Neural Regen Res | 2026 | 42199099 | PubTator, text mining | PubMed |
| RUNX1-mediated repression of miR-24 promotes hepatic stellate cell activation and liver fibrosis by targeting the ALK4/Smad3 signaling pathway. | Front Genet | 2026 | 42137245 | PubTator, text mining | PubMed |
| Growth differentiation factor-11 stimulates human extravillous trophoblast cell invasion by upregulating Slug-mediated N-cadherin expression. | Placenta | 2026 | 42097099 | PubTator, text mining | PubMed |
| Genome-wide association study of myopia progression in Chinese adolescents and application of polygenic risk score prediction. | Front Chem | 2026 | 42094695 | PubTator, text mining | PubMed |
| Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review). | Int J Oncol | 2026 | 41860028 | PubTator, text mining | PubMed |
1 to 10 of 1,784
See all 1,784 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/91
GET https://conductscience.org/api/genes/v1/91/patents?page=2