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USP8: ubiquitin specific peptidase 8
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Gene · 9101

Papers1,448

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,448

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TitleJournalYearPMIDFound bySource
Deubiquitinase USP8 inhibits HIV-1 replication by suppressing Tat-mediated viral transactivation.J Virol202642803586PubTator, text miningPubMed
Proteome-wide Mendelian randomization and transcriptome analysis of a novel osteoarthritis blood-targeting USP8, single-cell model and experimental validation.Int Immunopharmacol202642772042PubTator, text miningPubMed
Somatic genetic alterations in pituitary neuroendocrine tumors.Endocr Relat Cancer202642565462PubTator, text miningPubMed
USP8 promotes the progression of sepsis-induced acute lung injury by interacting with the USP24 to suppress PGC-1α deubiquitination and expression.Redox Biol202642537474PubTator, text miningPubMed
Targeting USP8 with odoroside A regulates LXRβ-mediated fatty acid metabolic reprogramming against colorectal cancer.Acta Pharmacol Sin202642420594PubTator, text miningPubMed
Targeting SLK protects against cerebral ischemia-reperfusion injury by regulating USP8-mediated HIF-1α stabilization and RhoA/ROCK activation.Cell Mol Biol Lett202642387373PubTator, text miningPubMed
Sbno1 and Usp8 Cooperate to Enhance Notch Signaling in Regulating Neural Stem Cells.Dev Growth Differ202642323189PubTator, text miningPubMed
Distinct genetic alterations drive Cushing disease vs silent corticotroph adenomas.J Clin Endocrinol Metab202642273717PubTator, text miningPubMed
Molecular profile of Cushing's syndrome.Vitam Horm202642236012PubTator, text miningPubMed
Real-time PCR-based intraoperative molecular boundary diagnosis of corticotroph pituitary neuroendocrine tumors.J Neurosci Methods202642214473PubTator, text miningPubMed
CAF-derived exosomes drive trastuzumab resistance in HER2-positive breast cancer via YAP-USP8-HER2 axis activation.Breast Cancer Res202642141445PubTator, text miningPubMed
USP8/GPX4-based live-cell quantitative FRET imaging for ferroptosis drug screening.Biochim Biophys Acta Mol Cell Res202642140526PubTator, text miningPubMed
miR-511-3p dysregulation-mediated AKT3/USP8 signaling imbalance: a molecular bridge between neuroinflammation and PSCI.Front Immunol202642131328PubTator, text miningPubMed
The Sonic Hedgehog Pathway is Activated in Cushing's Disease with USP8 Mutations.Biochem Genet202642101757PubTator, text miningPubMed
Differential expression of POMC-processing genes in corticotroph tumors.Endocr Oncol202642078585PubTator, text miningPubMed
From stability to pathology: protein degradation pathways underlying synaptic proteins in neurological diseases.Neuroscience202642066889PubTator, text miningPubMed
Prevalence of germline variants in USP8, USP48, CABLES1 and PAM in patients with pituitary adenomas.Eur J Endocrinol202642045809PubTator, text miningPubMed
Expanding the Spectrum of Ubiquitin-specific Proteases-Fused Neoplasms: A Clinicopathologic and Molecular Study of USP2- and USP8-Rearranged Spindle Cell Tumors.Am J Surg Pathol202642017400PubTator, text miningPubMed
Late recurrence of Cushing disease with ubiquitin-specific protease 8 mutation 19 years after initial surgery.JCEM Case Rep202641971637PubTator, text miningPubMed
Genomic characterization of aggressiveness in pituitary neuroendocrine tumors.Neuro Oncol202641955313PubTator, text miningPubMed

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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